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肥胖患者经部分胸骨上段切开术行主动脉瓣置换术与传统主动脉瓣置换术的疗效比较。

Outcomes of aortic valve replacement via partial upper sternotomy versus conventional aortic valve replacement in obese patients.

作者信息

Welp Henryk A, Herlemann Isabell, Martens Sven, Deschka Heinz

机构信息

Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University Hospital Münster, Münster, Germany.

出版信息

Interact Cardiovasc Thorac Surg. 2018 Oct 1;27(4):481-486. doi: 10.1093/icvts/ivy083.

Abstract

OBJECTIVES

Excellent outcomes after minimally invasive aortic valve replacement (mini-AVR) have been reported. Therefore, mini-AVR has become a popular treatment option in many cardiac surgery centres. However, whether obese patients particularly benefit from mini-AVR remains unclear. The aim of the present study was to evaluate outcomes of AVR performed through partial upper sternotomy compared to AVR through a full sternotomy (full-AVR) in obese patients.

METHODS

We retrospectively reviewed the medical records of all patients who underwent isolated AVR at our institution, and 217 consecutive obese [body mass index (BMI) >30 kg/m2] patients were identified. Outcomes of the mini-AVR group were compared with the full-AVR group.

RESULTS

One hundred and twenty-six patients underwent mini-AVR and 91 patients had full-AVR. The mean age and BMI were 69.8 ± 10.4 years and 32.6 ± 3.1 kg/m2 in the mini-AVR group compared to 70.0 ± 10.5 years and 33.1 ± 3.0 kg/m2 in the full-AVR group. Mortality, myocardial infarction, stroke, renal failure and surgical site infections were equivalent. Mini-AVR was associated with decreased ventilation time [6 h (minimum, min 3 h; maximum, max 76 h) vs 8 h (min 3 h; max 340 h); P = 0.004], shorter intensive care unit (ICU) stay [2 days (min 1 day; max 25 days) vs 4 days (min 1 day; max 35 days); P = 0.031] and reduced transfusion requirements (26.5% vs 56.0%; P = 0.004). Total duration of hospital stay as well as postoperative pain levels were comparable.

CONCLUSIONS

Patient safety was not affected by mini-AVR. Significant benefits in terms of decreased transfusion requirements, ventilator times and ICU times were found in the mini-AVR group. Consequently, mini-AVR, performed through partial upper sternotomy, should also be routinely offered to obese patients.

摘要

目的

已有报道称微创主动脉瓣置换术(mini-AVR)术后效果良好。因此,mini-AVR已成为许多心脏外科中心常用的治疗选择。然而,肥胖患者是否能从mini-AVR中特别获益仍不清楚。本研究的目的是评估肥胖患者经部分上胸骨切开术进行主动脉瓣置换术(AVR)与经全胸骨切开术(全AVR)进行AVR的效果。

方法

我们回顾性分析了在我院接受单纯AVR的所有患者的病历,确定了217例连续的肥胖患者[体重指数(BMI)>30 kg/m²]。将mini-AVR组的结果与全AVR组进行比较。

结果

126例患者接受了mini-AVR,91例患者接受了全AVR。mini-AVR组的平均年龄和BMI分别为69.8±10.4岁和32.6±3.1 kg/m²,而全AVR组为70.0±10.5岁和33.1±3.0 kg/m²。死亡率、心肌梗死、中风、肾衰竭和手术部位感染情况相当。mini-AVR与通气时间缩短相关[6小时(最小值3小时;最大值76小时)对8小时(最小值3小时;最大值340小时);P = 0.004],重症监护病房(ICU)住院时间缩短[2天(最小值1天;最大值25天)对4天(最小值1天;最大值35天);P = 0.031],输血需求减少(26.5%对56.0%;P = 0.004)。住院总时长以及术后疼痛程度相当。

结论

mini-AVR不影响患者安全。mini-AVR组在减少输血需求、呼吸机使用时间和ICU时间方面有显著益处。因此,经部分上胸骨切开术进行的mini-AVR也应常规应用于肥胖患者。

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