药物递送系统对哮喘儿童治疗依从性影响的综述。
A review of the effects of medication delivery systems on treatment adherence in children with asthma.
作者信息
Cohn Robert C
机构信息
Department of Pediatrics, MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
出版信息
Curr Ther Res Clin Exp. 2003 Jan;64(1):34-44. doi: 10.1016/S0011-393X(03)00002-X.
BACKGROUND
A patient's adherence to an appropriate treatment regimen is necessary to minimize morbidity and mortality associated with childhood asthma. Many factors influence the success of treatment adherence.
OBJECTIVE
The goal of this article was to examine the effect of the mode of medication delivery on the success of treatment adherence in children with asthma.
METHODS
Relevant clinical studies were identified through a MEDLINE search of articles published from 1966 to 2002, using the search terms adherence, aerosol, asthma, children, compliance, dry powder inhaler, metered-dose inhaler, nebulizer, and pediatric.
RESULTS
A relationship seems to exist between treatment adherence and the type of medication delivery system used in childhood asthma. The highest rates of adherence appear to be associated with oral medications.
CONCLUSIONS
Clinicians should consider the mode of medication delivery as 1 factor that can influence the success of treatment adherence.
背景
患者坚持适当的治疗方案对于将儿童哮喘相关的发病率和死亡率降至最低至关重要。许多因素会影响治疗依从性的成功。
目的
本文的目的是研究药物递送方式对哮喘儿童治疗依从性成功的影响。
方法
通过对1966年至2002年发表的文章进行MEDLINE检索，使用检索词依从性、气雾剂、哮喘、儿童、依从性、干粉吸入器、定量吸入器、雾化器和儿科，确定相关临床研究。
结果
治疗依从性与儿童哮喘中使用的药物递送系统类型之间似乎存在关联。依从率最高的似乎与口服药物有关。
结论
临床医生应将药物递送方式视为可影响治疗依从性成功的一个因素。
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