El Shahat Khaled, El Saeid Aziza, Attalla Ehab, Yassin Adel
Radiation Oncology Department, Faculty of Medicine, Al Azhar University, Egypt.
Biophysics Branch, Physics Department, Faculty of Sciences (Girls), Al Azhar University, Egypt.
ISRN Oncol. 2014 May 6;2014:901436. doi: 10.1155/2014/901436. eCollection 2014.
To achieve tumor control for radiotherapy, a dose distribution is planned which has a good chance of sterilizing all cancer cells without causing unacceptable normal tissue complications. The aim of the present study was to achieve an accurate calculation of dose for small field dimensions and perform this by evaluating the accuracy of planning system calculation. This will be compared with real measurement of dose for the same small field dimensions using different detectors. Practical work was performed in two steps: (i) determination of the physical factors required for dose estimation measured by three ionization chambers and calculated by treatment planning system (TPS) based on the latest technical report series (IAEATRS-398) and (ii) comparison of the calculated and measured data. Our data analysis for small field is irradiated by photon energy matched with the data obtained from the ionization chambers and the treatment planning system. Radiographic films were used as an additional detector for the obtained data and showed matching with TPS calculation. It can be concluded that studied small field dimensions were averaged 6% and 4% for 6 MV and 15 MV, respectively. Radiographic film measurements showed a variation in results within ±2% than TPS calculation.
为实现放射治疗的肿瘤控制,需规划一种剂量分布,这种分布有很大机会杀灭所有癌细胞,同时又不会引发不可接受的正常组织并发症。本研究的目的是精确计算小射野尺寸的剂量,并通过评估计划系统计算的准确性来实现这一目标。这将与使用不同探测器对相同小射野尺寸进行剂量的实际测量结果进行比较。实际工作分两步进行:(i)确定由三个电离室测量并由治疗计划系统(TPS)根据最新技术报告系列(IAEA - TRS - 398)计算剂量估计所需的物理因素;(ii)比较计算数据和测量数据。我们对小射野的数据分析是在与从电离室和治疗计划系统获得的数据相匹配的光子能量照射下进行的。使用射线照相胶片作为所获数据的额外探测器,其结果与TPS计算结果相符。可以得出结论,所研究的小射野尺寸在6兆伏和15兆伏时分别平均为6%和4%。射线照相胶片测量结果与TPS计算结果相比,变化在±2%以内。