Chittal Prerana, Babu Abraham Samuel, Lavie Carl J
1Department of Physiotherapy, School of Allied Health Sciences, Manipal University , Manipal, Karnataka.
COPD. 2015 Feb;12(1):14-8. doi: 10.3109/15412555.2014.915934. Epub 2014 Jun 19.
The role of obesity and its influence on mortality in the general population has been well established. However, over the last decade, there has been substantial focus on the paradox that exists among the obese with various chronic diseases, where overweight and at least mild-moderately obese with these chronic diseases appear to have a better prognosis than do their leaner counterparts. Among them, congestive heart failure and coronary heart disease have received considerable attention. However, the influence of the obesity paradox on outcomes among patients with chronic obstructive pulmonary disease (COPD), including those requiring long-term oxygen therapy, has not been elucidated. This paper highlights the current research in this area and brings to light the lacunae that exists with regard to this paradox in COPD.
肥胖在普通人群中的作用及其对死亡率的影响已得到充分证实。然而，在过去十年中，人们大量关注肥胖人群中存在的各种慢性疾病的矛盾现象，即患有这些慢性疾病的超重和至少轻度至中度肥胖者似乎比体重较轻者预后更好。其中，充血性心力衰竭和冠心病受到了相当多的关注。然而，肥胖悖论对慢性阻塞性肺疾病（COPD）患者结局的影响，包括那些需要长期氧疗的患者，尚未得到阐明。本文重点介绍了该领域的当前研究，并揭示了COPD中关于这一悖论存在的空白。
