Foppa C, Martinek L, Arnaud J P, Bergamaschi R
Division of Colon and Rectal Surgery, State University of New York, Stony Brook, New York, USA.
Colorectal Dis. 2014 Oct;16(10):809-14. doi: 10.1111/codi.12689.
Studies have shown that recurrence rates of full-thickness rectal prolapse (FTRP) 5 years after surgery can quadruple at 10 years. This study aimed to evaluate the impact of laparoscopic suture rectopexy for FTRP on recurrence rates and functional outcome at a median follow up of 10 years.
Prospectively collected data for patients who underwent laparoscopic suture rectopexy for FTRP between 1993 and 2006 were analysed. Laparoscopic rectopexy consisted of circumferential mobilization of the rectum down to the levator followed by suture suspension to promontory. Patients with preexisting constipation or who were unfit for general anaesthesia were not included. Incontinence, quality of life and constipation were assessed by validated scores. Recurrence-free curves were generated using the Kaplan-Meier method.
One hundred and seventy-nine patients with a median age of 62 (15-93) years including 174 women and five men underwent laparoscopic suture rectopexy. There was no mortality. The 30-day complication rate was 4% (partial transection of the left ureter, pneumonia, urinary tract infection, urinary retention, superficial surgical site infection). Data on 172 patients (96%) were available at follow up. There were 10 recurrences of FTRP at 5-year follow up giving a crude recurrence rate of 6%. The actuarial 10-year recurrence rate was 20% (95% CI, 10.8-20.1). Follow-up continence (P < 0.0001) and quality of life were better than preoperatively: lifestyle (P < 0.001), coping (P < 0.001), self-perception (P < 0.005), embarrassment (P < 0.06). Constipation was unchanged.
Laparoscopic suture rectopexy led to few complications, a recurrence rate of 20%, improved continence and quality of life with no worsening of constipation at 10 years.
研究表明,全层直肠脱垂(FTRP)术后5年的复发率在10年时可能会增至四倍。本研究旨在评估腹腔镜缝合直肠固定术治疗FTRP对复发率及功能结局的影响,随访时间中位数为10年。
对1993年至2006年间接受腹腔镜缝合直肠固定术治疗FTRP的患者的前瞻性收集数据进行分析。腹腔镜直肠固定术包括将直肠向下游离至肛提肌水平,然后缝合悬吊至岬部。既往有便秘或不适合全身麻醉的患者未纳入。通过经过验证的评分评估失禁、生活质量和便秘情况。采用Kaplan-Meier方法生成无复发生存曲线。
179例患者接受了腹腔镜缝合直肠固定术,中位年龄62(15 - 93)岁,其中174例女性,5例男性。无死亡病例。30天并发症发生率为4%(左侧输尿管部分横断、肺炎、尿路感染、尿潴留、手术切口浅表感染)。172例患者(96%)有随访数据。5年随访时有10例FTRP复发,粗复发率为6%。10年精算复发率为20%(95%CI,10.8 - 20.1)。随访时的控便能力(P < 0.0001)和生活质量优于术前:生活方式(P < 0.001)、应对能力(P < 0.001)、自我认知(P < 0.005)、尴尬程度(P < 0.06)。便秘情况无变化。
腹腔镜缝合直肠固定术并发症少,10年复发率为20%,控便能力和生活质量得到改善,便秘情况未恶化。