Nakashima Chisa, Tanizaki Hideaki, Otsuka Atsushi, Miyachi Yoshiki, Kabashima Kenji
Kyoto University Graduate School of Medicine, Japan.
Dermatol Online J. 2014 Jun 15;20(6):13030/qt9xp4640d.
Prurigo nodularis (PN) is an eruption of lichenified or excoriated nodules related to intractable pruritus. A few reports have shown that a 308-nm excimer lamp/laser (EL) is effective for intractable PN. Herein, we report on two cases of intractable prurigo nodularis successfully treated with a new EL equipped with a filter to cut wavelengths shorter than 297 nm. Because this newly developed EL yields a therapeutic effect with low cumulative dosages of UV and a lower risk of DNA damage, it can be a new treatment option for intractable PN.
结节性痒疹（PN）是一种与顽固性瘙痒相关的苔藓化或抓破性结节性皮疹。一些报告表明，308纳米准分子灯/激光（EL）对顽固性PN有效。在此，我们报告两例顽固性结节性痒疹患者成功接受一种配备滤光片以滤除短于297纳米波长的新型EL治疗的病例。由于这种新开发的EL以低累积紫外线剂量产生治疗效果且DNA损伤风险较低，它可以成为顽固性PN的一种新的治疗选择。
