Faculty of Medicine, Finis Terrae University, Santiago, Chile.
Faculty of Medicine, University of Chile, Santiago, Chile.
An Bras Dermatol. 2024 Nov-Dec;99(6):887-894. doi: 10.1016/j.abd.2023.12.007. Epub 2024 Aug 5.
Excimer light is a subtype of NB-UVB that emits a 308 nm wavelength, and can provide targeted phototherapy treatment. The absorption of 308 nm light by skin cells leads to therapeutic response in various common and ultraviolet-responsive skin diseases, such as psoriasis and vitiligo, and photo-resistant skin diseases such as prurigo nodularis, localized scleroderma, genital lichen sclerosis, and granuloma annulare, cutaneous T-cell lymphomas, among others. Excimer light has few adverse reactions and overall is well tolerated by patients, furthermore, it can be performed in places that are difficult to access. This article aims to explain the therapeutic bases and applications of excimer light in current dermatology.
准分子光属于中波紫外线的一种，波长为 308nm，可提供靶向光疗。308nm 光被皮肤细胞吸收，可在各种常见和紫外线反应性皮肤病（如银屑病和白癜风）以及光抗性皮肤病（如结节性痒疹、局限性硬皮病、生殖器硬化性苔藓、环状肉芽肿、皮肤 T 细胞淋巴瘤等）中产生治疗反应。准分子光不良反应少，患者总体耐受良好，此外，还可在难以到达的部位进行治疗。本文旨在解释准分子光在当前皮肤科中的治疗基础和应用。
