Sandoval Mauricio, Giesen Laura, Cataldo Karina, Gonzalez Sergio
*Department of Dermatology, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile; and †Department of Pathology, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile.
Am J Dermatopathol. 2015 Jul;37(7):587-9. doi: 10.1097/DAD.0000000000000139.
Postirradiation pseudosclerodermatous panniculitis presents as an erythematous indurated plaque, on a previously irradiated area. Histopathologically, thick and sclerotic septa and inflammatory infiltrate with foamy histiocytes and adiponecrosis are seen. To date, 12 cases have been reported worldwide. Hereby, we report the case of a 68-year-old woman who developed an indurated painful erythematous plaque on her right leg after radiotherapy for a soft tissue sarcoma, with a septal panniculitis and lobular adiponecrosis on histopathological examination. This is the 13th case reported and the second of extrathoracic location.
放疗后假性硬皮病样脂膜炎表现为先前接受过放疗区域出现的红斑性硬结斑块。组织病理学上可见增厚且硬化的间隔以及伴有泡沫状组织细胞和脂肪坏死的炎性浸润。迄今为止，全球已报道12例。在此，我们报告一例68岁女性病例，该患者因软组织肉瘤接受放疗后右下肢出现硬结性疼痛红斑斑块，组织病理学检查显示为间隔性脂膜炎和小叶性脂肪坏死。这是报道的第13例病例，也是胸外部位的第二例。
