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[主要抗结核药物的治疗效果:通过抗菌谱进行评估]

[Therapeutic efficacy of the principal antitubercular drugs: an evaluation by antibiogram].

作者信息

Cremonte L G, Mantellini E

机构信息

Divisione di Medicina Generale, Ospedale Civile, Novi Ligure.

出版信息

Minerva Med. 1989 Feb;80(2):153-6.

PMID:2494591
Abstract

Pulmonary and extrapulmonary tuberculosis is still encountered in clinical practice, sometimes in forms that are difficult to categorize nosographically. In this study, the therapeutic efficacy of the 6 main antitubercular drugs (rifampicin, streptomycin, isoniazide, ethambutol, kanamycin, para-aminosalicylic acid) in 20 patients with early TB of the lungs was assessed on the basis of antibiogram findings. Para-aminosalicylic acid was found to be the least effective; isoniazide, rifampicin and streptomycin were reasonably so; both kanamycin and ethambutol were extremely effective.

摘要

肺内和肺外结核病在临床实践中仍有出现,有时其形式在疾病分类学上难以归类。在本研究中,根据药敏试验结果评估了6种主要抗结核药物(利福平、链霉素、异烟肼、乙胺丁醇、卡那霉素、对氨基水杨酸)对20例早期肺结核患者的治疗效果。结果发现对氨基水杨酸效果最差;异烟肼、利福平和链霉素效果尚可;卡那霉素和乙胺丁醇都极为有效。

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