Nudleman Eric, Witmer Matthew T, Kiss Szilard, Williams George A, Wolfe Jeremy D
*Associated Retinal Consultants, Royal Oak, Michigan; †Department of Ophthalmology, Weill Cornell Medical College, New York, New York; and ‡Department of Ophthalmology, Oakland University William Beaumont School of Medicine, Beaumont Eye Institute, Royal Oak, Michigan.
Retina. 2014 Oct;34(10):2128-32. doi: 10.1097/IAE.0000000000000198.
To report an association between central serous chorioretinopathy (CSCR) and exogenous testosterone therapy.
This is a retrospective case series from two institutions. Patients who presented with fluorescein angiography and optical coherence tomography findings consistent with CSCR were included. All patients were concurrently being treated with exogenous testosterone therapy and lacked other known risk factors for CSCR.
Nine patients presented with CSCR after beginning exogenous testosterone therapy. Two patients stopped therapy with resolution of symptoms and subretinal fluid.
Exogenous testosterone may be an independent risk factor for the development of CSCR.
报告中心性浆液性脉络膜视网膜病变(CSCR)与外源性睾酮治疗之间的关联。
这是一项来自两家机构的回顾性病例系列研究。纳入了荧光素血管造影和光学相干断层扫描结果符合CSCR的患者。所有患者均同时接受外源性睾酮治疗,且缺乏其他已知的CSCR危险因素。
9例患者在外源性睾酮治疗开始后出现CSCR。2例患者停止治疗后症状缓解,视网膜下液吸收。
外源性睾酮可能是CSCR发生的独立危险因素。