Bussel Igor I, Lally David R, Waheed Nadia K
Ophthalmic Surg Lasers Imaging Retina. 2014 Nov-Dec;45(6):589-91. doi: 10.3928/23258160-20141118-16.
Central serous chorioretinopathy (CSCR) is an idiopathic disease associated with states of hypercortisolism that causes fluid to collect under the retina resulting in visual impairment. The authors describe an otherwise healthy female patient who presented with headaches and blurry vision after a 2-month history of excessive daily consumption of diindolylmethane (DIM), an over-the-counter estrogen modulator medication used to treat facial acne. Imaging demonstrated asymmetric, bilateral CSCR with active leakage in the left eye. She was instructed to discontinue DIM and reported that visual improvement began 2 weeks after, with resolution to baseline after 8 weeks.
中心性浆液性脉络膜视网膜病变（CSCR）是一种与高皮质醇血症相关的特发性疾病，可导致液体在视网膜下积聚，从而造成视力损害。作者描述了一名原本健康的女性患者，该患者在每日过量服用二吲哚甲烷（DIM）两个月后出现头痛和视力模糊，DIM是一种用于治疗面部痤疮的非处方雌激素调节剂药物。影像学检查显示双侧不对称性CSCR，左眼有活动性渗漏。她被要求停用DIM，据报告，2周后视力开始改善，8周后恢复至基线水平。
