Zurich University Psychiatric Hospital, Switzerland.
Int J Psychiatry Clin Pract. 1998;2(2):115-9. doi: 10.3109/13651509809115343.
The mortality of patients with mood disorders is elevated as a consequence not only of suicides and accidents but also of cardiovascular and other diseases - for instance, hypothyroidism and hyperthyroidism. Long-term medication can reduce suicides by two-thirds and can probably reduce non-suicidal mortality also. This long-term study of 406 hospital admissions recruited between 1959 and 1963 and followed up until 1991 suggests that not only lithium (as reported in the literature), but also neuroleptics and antidepressants may have such beneficial effects.
心境障碍患者的死亡率升高，不仅是由于自杀和意外，还由于心血管和其他疾病——例如，甲状腺功能减退和甲状腺功能亢进。长期药物治疗可以将自杀减少三分之二，可能也能降低非自杀性死亡率。这项对 406 名 1959 年至 1963 年住院患者的长期研究进行了随访，直到 1991 年，结果表明，不仅锂（如文献所述），而且抗精神病药和抗抑郁药也可能有这种有益的效果。
