Yunusa Mufutau A, Njoku Chibueze H, Obembe Ayo
Niger J Med. 2014 Jan-Mar;23(1):33-9.
Adherence to treatment is important and relevant in HIV treatment. Previous studies in sub Sahara Africa and south western Nigeria reported that psychiatric morbidity influence treatment adherence. The present study was to examine treatment adherence among the male and the female patients with HIV infection and the effect of socioeconomic factors and psychiatric morbidity on treatment adherence.
A total of 159 patients which comprised of 48 male and 111 female who were eligible for this cross sectional prospective study were included having given their consent to participate. Questionnaire relating to socioeconomic factors and treatment adherence were administered. Psychiatric morbidity was assessed using HADS. Data was analyzed with SPSS for windows version 16.0.
Treatment adherence was poor in 5.3% of the patients. The male patients had slightly better adherence than the female patients. Factors associated with poor treatment adherence include poor clinic attendance, presence of anxiety symptoms in males and poor education attainment in females.
Treatment adherence is related to socioeconomic factors and psychiatric morbidity. Treatment protocol in which mental health and detailed socioeconomic circumstance of patient is an integral part should be encouraged.
在艾滋病治疗中，坚持治疗至关重要且意义重大。此前在撒哈拉以南非洲和尼日利亚西南部开展的研究表明，精神疾病会影响治疗依从性。本研究旨在调查感染艾滋病毒的男性和女性患者的治疗依从性，以及社会经济因素和精神疾病对治疗依从性的影响。
共有159名患者参与了这项横断面前瞻性研究，其中包括48名男性和111名女性，他们均已同意参与研究。发放了与社会经济因素和治疗依从性相关的问卷。使用医院焦虑抑郁量表（HADS）评估精神疾病。数据采用SPSS for windows 16.0版本进行分析。
5.3%的患者治疗依从性较差。男性患者的依从性略好于女性患者。与治疗依从性差相关的因素包括就诊不规律、男性存在焦虑症状以及女性教育程度低。
治疗依从性与社会经济因素和精神疾病有关。应鼓励采用将患者心理健康和详细社会经济状况纳入其中的治疗方案。
