Chen Rong, Wang Cong, Yan Qing-Ya
Zhongguo Zhen Jiu. 2014 Apr;34(4):355-8.
To investigate the effectiveness of polycystic ovary syndrome (PCOS) of damp-phlegm constitution treated with embedding therapy on back-shu points and front-mu points and needle-pricking therapy on Sifeng (EX-UE 10).
Eighty-five patients were randomly divided into 2 groups of observation group (42 cases) and control group (43 cases). Embedding therapy on back-shu points and front-mu points and needle-pricking therapy on Sifeng (EX-UE 10) were applied to the observation group. Points such as Zhongwan (CV 12), Guanyuan (CV 4), Tianshu (ST 25), Zhangmen (LR 13), Jingmen (GB 25), Qimen (LR 14), Ganshu (BL 18), Weishu (BL 21), Pishu (BL 20), Shenshu (BL 23), Dachangshu (BL 25) and Xiaochangshu (BL 27), etc. were adopted for embedding therapy. At the same time, needle-pricking therapy on Sifeng (EX-UE 10) was also applied once a week. 0. 5 g metformin hydrochloride tablet was given to the control group, once a day for the first week, and twice a day from the second week. Estimation on therapeutic effect was made for both groups after 3 months treatment. Change of symptoms and signs scores, fasting insulin (FINS), 2 hour insulin after meal (2hINS) and insulin resistance index (HOMA-IR) of both groups before and after treatment were observed, and therapeutic effect estimated.
The total effective rate of the observation group is 97. 6% (41/42), and that of the control group was 95. 4% (41/43). There was no significant difference between the two groups (P>0. 05). Scores of symptoms and signs after treatment were significantly improved in both groups (all P<0. 01), and the observation group was better than the control group (7.01+/-4.23 vs 8. 47+/-2. 82,P<0. 05). Compare with those before the treatment, FINS, 2hINS and HOMA-IR after the treatment were all decreased in both groups (all P<0. 05). The comparison between the two groups showed that differences of FIN had no statistic significance (P>0. 05) after the treatment, while both differences of 2hINS and HOMA-IR had statistic significance [ 2hlNS: (443. 531+/- 93. 90) pmol/L vs (621.29+/-93. 87) pmol/L ; HOMA-IR: 4. 88+/-0. 30 vs 5.06+/-0. 32, both P<0. 05]. The improvement of 2hINS and HOMA-IR in the observation group was better than that of the control group.
Treatment of PCOS of damp-phlegm constitution with embedding therapy on back-shu points and front-mu points and needle-pricking therapy on Sifeng (EX-UE 10) have positive effect, which can effectively reduce the insulin resistance, meanwhile, reduce the side-effects of western medication.
探讨背俞穴与募穴埋线配合四缝穴(EX-UE 10)点刺治疗痰湿体质多囊卵巢综合征(PCOS)的疗效。
将85例患者随机分为观察组42例和对照组43例。观察组采用背俞穴与募穴埋线配合四缝穴(EX-UE 10)点刺治疗。埋线选取中脘(CV 12)、关元(CV 4)、天枢(ST 25)、章门(LR 13)、京门(GB 25)、期门(LR 14)、肝俞(BL 18)、胃俞(BL 21)、脾俞(BL 20)、肾俞(BL 23)、大肠俞(BL 25)、小肠俞(BL 27)等穴位。同时,四缝穴(EX-UE 10)点刺治疗每周1次。对照组给予盐酸二甲双胍片0.5 g,第1周每天1次,第2周起每天2次。两组均治疗3个月后进行疗效评估。观察两组治疗前后症状体征评分、空腹胰岛素(FINS)、餐后2小时胰岛素(2hINS)及胰岛素抵抗指数(HOMA-IR)的变化,并评估疗效。
观察组总有效率为97.6%(41/42),对照组为95.4%(41/43)。两组比较差异无统计学意义(P>0.05)。两组治疗后症状体征评分均显著改善(均P<0.01),且观察组优于对照组(7.01±4.23 vs 8.47±2.82,P<0.05)。两组治疗后FINS、2hINS及HOMA-IR均较治疗前降低(均P<0.05)。两组比较,治疗后FIN差异无统计学意义(P>0.05),而2hINS及HOMA-IR差异均有统计学意义[2hINS:(443.531±93.90)pmol/L vs(621.29±93.87)pmol/L;HOMA-IR:4.88±0.30 vs 5.06±0.32,均P<0.05]。观察组2hINS及HOMA-IR的改善情况优于对照组。
背俞穴与募穴埋线配合四缝穴(EX-UE 10)点刺治疗痰湿体质PCOS有积极作用,能有效降低胰岛素抵抗,同时减少西药副作用。