Rockwell S, Kelley M
Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06510-8040.
Radiother Oncol. 1989 Jan;14(1):49-53. doi: 10.1016/0167-8140(89)90008-x.
The ability of intravenously-injected mouse mammary tumor cells to form lung tumors is increased by irradiation of the thorax 24 h previously. We examined the effects of treatment with a perfluorochemical emulsion (Fluosol-DA, 20%) plus carbogen before and during irradiation on the radiation-induced enhancement of lung nodule formation. We found no evidence that treatment with Fluosol plus carbogen altered the development of tumor nodules in irradiated mouse lungs.
预先24小时照射胸部可增强静脉注射的小鼠乳腺肿瘤细胞形成肺肿瘤的能力。我们研究了在照射前及照射期间用全氟化学乳剂(氟碳乳剂-DA,20%)加二氧化碳治疗对辐射诱导的肺结节形成增强作用的影响。我们没有发现证据表明氟碳乳剂加二氧化碳治疗会改变受照射小鼠肺部肿瘤结节的发展。