Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, 11100 Euclid Avenue, LTR B181 Cleveland, OH 44106, USA.
Future Oncol. 2014 May;10(7):1299-310. doi: 10.2217/fon.14.13.
Stereotactic body radiotherapy (SBRT) has been used extensively in patients with lung, liver and spinal tumors, and the treatment outcomes are very favorable. For certain conditions such as medically inoperable stage I non-small-cell lung cancer, liver and lung oligometastases, primary liver cancer and spinal metastases, SBRT is regarded as one of the standard therapies. In the recent years, the use of SBRT has been extended to other disease conditions and sites such as recurrent head and neck cancer, renal cell carcinoma, prostate cancer, adrenal metastasis, pancreatic cancer, gynecological malignancies, spinal cord compression, breast cancer, and stage II-III non-small-cell lung cancer. Preliminary data in the literature show promising results but the follow-up intervals are short for most studies. This paper will provide an overview of these emerging applications.
立体定向体部放疗（SBRT）已广泛应用于肺、肝和脊柱肿瘤患者，其治疗效果非常理想。对于某些情况，如无法手术的 I 期非小细胞肺癌、肝和肺寡转移、原发性肝癌和脊柱转移，SBRT 被视为标准治疗之一。近年来，SBRT 的应用已扩展到其他疾病状况和部位，如复发性头颈部癌症、肾细胞癌、前列腺癌、肾上腺转移、胰腺癌、妇科恶性肿瘤、脊髓压迫、乳腺癌和 II-III 期非小细胞肺癌。文献中的初步数据显示出有希望的结果，但大多数研究的随访时间都很短。本文将对这些新出现的应用进行综述。
