Andersen Melissa N, Dore-Stites Dawn, Gleit Rebecca, Lopez M James, Fredericks Emily M
C.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of MichiganC.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of MichiganC.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of Michigan.
C.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of MichiganC.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of MichiganC.S. Mott Children's Hospital, University of Michigan Medical School, Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, Division of Pediatric Gastroenterology, Department of Pediatrics and Communicable Diseases, and Division of Child Behavioral Health, Child Health Evaluation and Research (CHEAR) Unit, Department of Pediatrics and Communicable Diseases, University of Michigan
J Pediatr Psychol. 2014 Aug;39(7):735-42. doi: 10.1093/jpepsy/jsu037. Epub 2014 Jun 18.
To investigate the relationship between sleep disturbance in children with liver transplants and parent and family health-related quality of life (HRQOL).
47 parents of children with liver transplants completed measures of child sleep and family HRQOL. Relationships between sleep and HRQOL and differences in HRQOL between groups with scores above and below the cutoff on a pediatric sleep measure were examined.
Parents endorsed higher rates of sleep-related breathing disorder (SRBD) and restless legs syndrome and periodic limb movements during sleep (RLS/PLMS) and lower HRQOL compared with published data. Significant correlations were found between SRBD and RLS/PLMS and HRQOL, and significant group differences in HRQOL were found between groups above and below the cutoff for behavior problems and RLS/PLMS.
There are significant relationships between symptoms of SRBD and RLS/PLMS in children with liver transplants and family HRQOL. Behavior problems may account for these strong relationships.
探讨肝移植儿童睡眠障碍与父母及家庭健康相关生活质量（HRQOL）之间的关系。
47名肝移植儿童的父母完成了儿童睡眠和家庭HRQOL的测量。研究了睡眠与HRQOL之间的关系，以及儿童睡眠测量得分高于和低于临界值的两组之间HRQOL的差异。
与已发表的数据相比，父母认可睡眠相关呼吸障碍（SRBD）、不宁腿综合征和睡眠期周期性肢体运动（RLS/PLMS）的发生率更高，HRQOL更低。发现SRBD与RLS/PLMS和HRQOL之间存在显著相关性，行为问题和RLS/PLMS临界值以上和以下的两组之间HRQOL存在显著差异。
肝移植儿童的SRBD和RLS/PLMS症状与家庭HRQOL之间存在显著关系。行为问题可能是这些密切关系的原因。
