Sun Jimin, Chai Chengliang, Lv Huakun, Lin Junfen, Wang Chengwei, Chen Enfu, Zhang Yanjun, Chen Zhiping, Liu Shelan, Gong Zhenyu, Jiang Jianmin
Zhejiang Provincial Centre for Disease Control and Prevention, Hangzhou, 310051, China.
Daishan Centre for Disease Control and Prevention, Daishan, China.
Int J Infect Dis. 2014 Aug;25:180-5. doi: 10.1016/j.ijid.2014.02.022. Epub 2014 Jun 16.
To summarize the epidemiological characteristics of severe fever with thrombocytopenia syndrome (SFTS) in Zhejiang Province, China.
A standardized questionnaire was used to collect information on demographic features, exposure history, clinical symptoms, and timelines of medical visits. Descriptive statistics were used to analyze the characteristics of SFTS.
A total of 65 cases of SFTS were identified in Zhejiang Province from 2011 to 2013, of whom 34 were male and 31 were female. The median age was 66 years and 60 cases occurred in persons aged ≥ 50 years. The majority (91%) of SFTS cases occurred between May and August. With regard to exposure history, patients had pursued outdoor activities (63%), had a history of exposure to a tick (68%) or tick bite (29%), bred domestic animals (31%), or had a history of exposure to a mouse (57%), and some patients had a multi-exposure history. Approximately 98.46% of patients were hospitalized, and symptoms of the illness included fever (98%), fatigue (71%), chills (51%), etc. Two family clusters occurred, although there was no person-to-person transmission.
In Zhejiang Province, SFTS is prevalent between May and August among elderly persons who live in hilly areas, and clinical features are not specific. More emphasis should be given to this disease and further training of medical personnel should be carried out to prevent misdiagnosis.
总结中国浙江省发热伴血小板减少综合征(SFTS)的流行病学特征。
采用标准化问卷收集人口统计学特征、暴露史、临床症状及就诊时间线等信息。运用描述性统计分析SFTS的特征。
2011年至2013年浙江省共确诊65例SFTS病例,其中男性34例,女性31例。年龄中位数为66岁,60例发生在年龄≥50岁的人群中。大多数(91%)SFTS病例发生在5月至8月。关于暴露史,患者有户外活动史(63%)、蜱暴露史(68%)或蜱叮咬史(29%)、饲养家畜史(31%)或鼠暴露史(57%),部分患者有多种暴露史。约98.46%的患者住院治疗,疾病症状包括发热(98%)、乏力(71%)、寒战(51%)等。出现了2个家庭聚集性病例,但未发生人传人现象。
在浙江省,SFTS于5月至8月在居住于山区的老年人中流行且临床特征不具特异性。应更加重视该病,并对医务人员进行进一步培训以防止误诊。