利用升主动脉与降主动脉直径之比分析二叶式主动脉瓣患者的升主动脉扩张情况。
The analysis of ascending aortic dilatation in patients with a bicuspid aortic valve using the ratio of the diameters of the ascending and descending aorta.
作者信息
Nakamura Yuki, Ryugo Masahiro, Shikata Fumiaki, Okura Masahiro, Okamura Toru, Yasugi Takumi, Izutani Hironori
机构信息
Department of Cardiovascular and Thoracic Surgery, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime 791-0295, Japan.
出版信息
J Cardiothorac Surg. 2014 Jun 19;9:108. doi: 10.1186/1749-8090-9-108.
BACKGROUND
A bicuspid aortic valve (BAV) is associated with premature valve dysfunction and abnormalities of the ascending aorta. The aim of our study was to assess the degree of ascending aortic dilatation by measuring the ratio of the dimension of the AAo to that of the descending aorta (DAo) using preoperative computerized tomography (CT).
METHODS
A review of our institutional clinical database identified 76 patients undergoing aortic valve replacement (AVR) and 73 control patients undergoing off-pump coronary artery bypass (OPCAB group) between September 2009 and April 2012.
RESULTS
There were 17 patients diagnosed with BAV (BAV group), and the remaining 59 patients had a tricuspid aortic valve (TAV group). The ratios of the dimensions of the AAo to that of the DAo (AAo/DAo) for each group were: BAV, 1.58 ± 0.25; TAV, 1.32 ± 0.11; and OPCAB, 1.29 ± 0.12. Interestingly, the AAo/DAo of the BAV group was significantly larger than that of the other groups.
CONCLUSIONS
Although progressive AAo dilatation for BAV is well documented, the diameter of the AAo is currently the only estimate of aortic dilatation. In this study, we report that the ratio of the AAo and DAo diameters in patients with BAV can be a new index for assessing the dilatation of the AAo and differentiating the patients with BAV from those with TAV.
背景
二叶式主动脉瓣(BAV)与瓣膜功能过早障碍及升主动脉异常有关。我们研究的目的是通过术前计算机断层扫描(CT)测量升主动脉(AAo)与降主动脉(DAo)直径之比,以评估升主动脉扩张程度。
方法
回顾我们机构的临床数据库,确定了2009年9月至2012年4月期间接受主动脉瓣置换术(AVR)的76例患者和接受非体外循环冠状动脉搭桥术的73例对照患者(OPCAB组)。
结果
有17例患者被诊断为BAV(BAV组),其余59例患者为三叶式主动脉瓣(TAV组)。每组AAo与DAo直径之比(AAo/DAo)分别为:BAV组,1.58±0.25;TAV组,1.32±0.11;OPCAB组,1.29±0.12。有趣的是,BAV组的AAo/DAo明显大于其他组。
结论
虽然BAV患者升主动脉逐渐扩张已有充分记录,但目前升主动脉直径是评估主动脉扩张的唯一指标。在本研究中,我们报告BAV患者的AAo与DAo直径之比可作为评估升主动脉扩张以及区分BAV患者与TAV患者的新指标。