Chua Yi-Yuan, Duong Hung A
Institute of Chemical and Engineering Sciences (ICES), Agency for Science, Technology and Research (A*STAR), 8, Biomedical Grove, Neuros, #07-01, Singapore 138665.
Chem Commun (Camb). 2014 Aug 7;50(61):8424-7. doi: 10.1039/c4cc02930e.
A catalyst system comprising Fe2(O(t)Bu)6 and an N-heterocyclic carbene ligand enables efficient syntheses of (hetero)biaryls from the reactions of aryl Grignard reagents with a diverse spectrum of (hetero)aryl chlorides. Amongst the alkoxide and amide counterions investigated, tert-butoxide was the most effective in inhibiting the homocoupling of arylmagnesiums.
一种由Fe2(O(t)Bu)6和一种氮杂环卡宾配体组成的催化剂体系，能够使芳基格氏试剂与多种（杂）芳基氯化物反应高效合成（杂）联芳基。在所研究的醇盐和酰胺抗衡离子中，叔丁醇盐在抑制芳基镁的均偶联方面最为有效。
