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用于放射治疗剂量计算算法的蒙特卡罗光子束建模与调试

Monte Carlo photon beam modeling and commissioning for radiotherapy dose calculation algorithm.

作者信息

Toutaoui A, Ait chikh S, Khelassi-Toutaoui N, Hattali B

机构信息

Département de Physique Médicale, Centre de Recherche Nucléaire d'Alger, 2 Bd Frantz Fanon BP399 Alger RP, Algiers, Algeria.

Service de Radiothérapie, Centre Pierre et Marie Curie, 1 Rue Battandier Place du 1er Mai, Algiers, Algeria.

出版信息

Phys Med. 2014 Nov;30(7):833-7. doi: 10.1016/j.ejmp.2014.05.007. Epub 2014 Jun 16.

Abstract

The aim of the present work was a Monte Carlo verification of the Multi-grid superposition (MGS) dose calculation algorithm implemented in the CMS XiO (Elekta) treatment planning system and used to calculate the dose distribution produced by photon beams generated by the linear accelerator (linac) Siemens Primus. The BEAMnrc/DOSXYZnrc (EGSnrc package) Monte Carlo model of the linac head was used as a benchmark. In the first part of the work, the BEAMnrc was used for the commissioning of a 6 MV photon beam and to optimize the linac description to fit the experimental data. In the second part, the MGS dose distributions were compared with DOSXYZnrc using relative dose error comparison and γ-index analysis (2%/2 mm, 3%/3 mm), in different dosimetric test cases. Results show good agreement between simulated and calculated dose in homogeneous media for square and rectangular symmetric fields. The γ-index analysis confirmed that for most cases the MGS model and EGSnrc doses are within 3% or 3 mm.

摘要

本研究的目的是对CMS XiO(医科达)治疗计划系统中实现的多网格叠加(MGS)剂量计算算法进行蒙特卡罗验证,该算法用于计算西门子Primus直线加速器产生的光子束所产生的剂量分布。直线加速器机头的BEAMnrc/DOSXYZnrc(EGSnrc软件包)蒙特卡罗模型用作基准。在研究的第一部分,BEAMnrc用于6兆伏光子束的调试,并优化直线加速器的描述以拟合实验数据。在第二部分中,在不同的剂量学测试案例中,使用相对剂量误差比较和γ指数分析(2%/2毫米,3%/3毫米)将MGS剂量分布与DOSXYZnrc进行比较。结果表明,在均匀介质中,方形和矩形对称野的模拟剂量与计算剂量之间具有良好的一致性。γ指数分析证实,在大多数情况下,MGS模型和EGSnrc剂量在3%或3毫米以内。

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