Biological and clinical significance of androgens and androgen receptor in prostate cancer.
作者信息
Koochekpour Shahriar
机构信息
Departments of Cancer Genetics and Urology, Center for Genetics and Pharmacology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA.
出版信息
Int J Biol Sci. 2014 Jun 10;10(6):652-3. doi: 10.7150/ijbs.9576. eCollection 2014.
Abstract
摘要
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本文引用的文献
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Androgen receptor mutations and polymorphisms in African American prostate cancer.非裔美国前列腺癌患者中的雄激素受体突变与多态性
Int J Biol Sci. 2014 Jun 5;10(6):643-51. doi: 10.7150/ijbs.8974. eCollection 2014.
2
Conversion of androgen receptor signaling from a growth suppressor in normal prostate epithelial cells to an oncogene in prostate cancer cells involves a gain of function in c-Myc regulation.雄激素受体信号从正常前列腺上皮细胞中的生长抑制因子转变为前列腺癌细胞中的致癌基因，这一过程涉及c-Myc调控功能的获得。
Int J Biol Sci. 2014 Jun 10;10(6):627-42. doi: 10.7150/ijbs.8756. eCollection 2014.
3
Androgen receptor activation in castration-recurrent prostate cancer: the role of Src-family and Ack1 tyrosine kinases.去势抵抗性前列腺癌中的雄激素受体激活：Src家族和Ack1酪氨酸激酶的作用
Int J Biol Sci. 2014 Jun 5;10(6):620-6. doi: 10.7150/ijbs.8264. eCollection 2014.
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Modulation of androgen receptor by FOXA1 and FOXO1 factors in prostate cancer.FOXA1和FOXO1因子对前列腺癌中雄激素受体的调节作用
Int J Biol Sci. 2014 Jun 5;10(6):614-9. doi: 10.7150/ijbs.8389. eCollection 2014.
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Beyond T and DHT - novel steroid derivatives capable of wild type androgen receptor activation.超越睾酮和双氢睾酮——能够激活野生型雄激素受体的新型甾体衍生物。
Int J Biol Sci. 2014 Jun 3;10(6):602-13. doi: 10.7150/ijbs.8844. eCollection 2014.
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Roles for the backdoor pathway of androgen metabolism in prostate cancer response to castration and drug treatment.雄激素代谢的旁路途径在前列腺癌对去势和药物治疗反应中的作用。
Int J Biol Sci. 2014 Jun 3;10(6):596-601. doi: 10.7150/ijbs.8780. eCollection 2014.
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Androgen receptor as a driver of therapeutic resistance in advanced prostate cancer.雄激素受体作为晚期前列腺癌治疗耐药的驱动因素。
Int J Biol Sci. 2014 Jun 1;10(6):588-95. doi: 10.7150/ijbs.8671. eCollection 2014.
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Targeting androgen receptor action for prostate cancer treatment: does the post-receptor level provide novel opportunities?靶向雄激素受体作用用于前列腺癌治疗：受体后水平是否提供了新的机遇？
Int J Biol Sci. 2014 Jun 1;10(6):576-87. doi: 10.7150/ijbs.8479. eCollection 2014.
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A road map to comprehensive androgen receptor axis targeting for castration-resistant prostate cancer.雄激素受体轴靶向治疗去势抵抗性前列腺癌的路线图
Cancer Res. 2013 Aug 1;73(15):4599-605. doi: 10.1158/0008-5472.CAN-12-4414. Epub 2013 Jul 25.
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