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儿童消化性溃疡穿孔单纯修补术后行幽门螺杆菌根除治疗。

Simple patch closure for perforated peptic ulcer in children followed by helicobacter pylori eradication.

机构信息

Turan Yildiz, Department of Pediatric Surgery, Sakarya University Medical Schools, Sakarya, Turkey.

Huri Tilla Ilce, Department of Nucleer Medicine, Sakarya University Medical Schools, Sakarya, Turkey.

出版信息

Pak J Med Sci. 2014 May;30(3):493-6. doi: 10.12669/pjms.303.4705.

Abstract

Peptic ulcer disease in children is rare. Therefore, the diagnosis can be missed until complications such as perforation or hemorrhage occur. Few reports have investigated the procedures and outcomes of children who have undergone operations for perforated duodenal ulcers. We report our experience with the modified Graham technique for perforated duodenal ulcers in nine children and review the literature. Methods : The records of patients operated on for a perforated duodenal ulcer in the last 8 years in two pediatric surgery centers were evaluated retrospectively. Patient demographics, symptoms, time to admission to hospital, operative findings, and postoperative clinical course were evaluated. Results : Nine children (mean age 13.2 years, range 6-170 years) were included. All patients were admitted in the first six hours after their abdominal pain started. In three patients, there was free air on plain x-rays, while the x-rays were normal in six. All perforations were located on the anterior surface of the first part of the duodenum and repaired with primary suturing and Graham patch omentoplasty. The recovery was uneventful in all patients. In five patients, urea breath tests were performed postoperatively for Helicobacter Pylori, and the results were positive. All patients underwent triple therapy with lansoprazole, amoxicillin, and clarithromycin. The mean follow-up time was 58 (range 3-94) months. Conclusions : Peptic ulcer perforation should be suspected in children who have acute abdominal pain and peritoneal signs, especially when their suffering is intense. The simple patch repair and postoperative triple therapy for Helicobacter Pylori are safe and satisfactory for treating peptic ulcer perforation in children.

摘要

儿童消化性溃疡病很少见。因此,在穿孔或出血等并发症发生之前,可能会误诊。很少有研究报道过接受十二指肠溃疡穿孔手术的儿童的治疗过程和结果。我们报告了 9 例采用 Graham 改良技术治疗十二指肠溃疡穿孔的经验,并对文献进行了回顾。

方法

回顾性分析过去 8 年在 2 个小儿外科中心接受手术治疗的十二指肠溃疡穿孔患者的病历。评估患者的人口统计学资料、症状、入院至穿孔的时间、手术发现和术后临床过程。

结果

共纳入 9 例患儿(平均年龄 13.2 岁,范围 6-170 岁)。所有患者在腹痛开始后 6 小时内入院。3 例患儿的平片上可见游离气体,6 例患儿的平片正常。所有穿孔均位于十二指肠第一段的前表面,采用一期缝合和 Graham 补丁网膜覆盖术进行修复。所有患者均顺利恢复。5 例患儿术后进行了尿素呼气试验检测幽门螺杆菌,结果阳性。所有患儿均接受兰索拉唑、阿莫西林和克拉霉素三联疗法治疗。平均随访时间为 58 个月(范围 3-94 个月)。

结论

对于有急性腹痛和腹膜征的儿童,尤其是腹痛剧烈时,应怀疑有消化性溃疡穿孔。简单的修补术和术后三联疗法治疗幽门螺杆菌对于儿童消化性溃疡穿孔是安全且满意的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ade6/4048492/fece2a9d80ff/pjms-30-493-g001.jpg

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