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19年小儿肾盂成形术治疗肾盂输尿管连接部梗阻的发生率趋势:一项儿科健康信息系统(PHIS)数据库研究

Trends in the Rates of Pediatric Pyeloplasty for Ureteropelvic Junction Obstruction over 19 Years: A PHIS Database Study.

作者信息

Akhavan Ardavan, Merguerian Paul A, Larison Cindy, Goldin Adam B, Shnorhavorian Margarett

机构信息

Division of Pediatric Urology, Seattle Children's Hospital, 4800 Sand Point Way, Seattle, WA 98105, USA.

Seattle Children's Research Institute, 1900 Ninth Ave, Seattle, WA 98101, USA.

出版信息

Adv Urol. 2014;2014:142625. doi: 10.1155/2014/142625. Epub 2014 May 13.

Abstract

Background. Over the past 20 years, the management of ureteropelvic junction obstruction (UPJ) has shifted. While many urologists note a decrease in the number of pyeloplasties performed over time, the nature of the change in practice has yet to be defined. In the current study, we utilize a national, multi-institutional database of children's hospitals to evaluate trends in patients undergoing pyeloplasty as well as the rate of surgical reconstruction over the past 20 years. Material/Methods. We queried the Pediatric Health Information System (PHIS) database for all children undergoing primary pyeloplasty between 1992 and 2011. Clinical variables, including age at time of surgery, gender, length of stay (LOS), and geographic region, were determined. Age-adjusted rate of repair was also calculated per 100,000 PHIS inpatients. Results. 6,013 patients were included in the study, of which 71.6% were male and 64.2% were under the age of 24 months at time of surgery. Over the study period, the median age at time of surgery increased from 2-4 months to 12-14 months (P < 0.01). LOS decreased from a median of 5 days to 2 days (P < 0.001). The rate of surgery increased by 10.6 pyeloplasties per 100,000 PHIS inpatients from 1992 to 2011 (P < 0.01). The highest rate of pyeloplasty was in the northeast. The increase in pyeloplasties performed from 1992 to 1999 was specific to children aged greater than 24 months, while rates stayed the same in infants younger than 2 years during the same time period. In contrast, from 1999 to 2011, the rate of pyeloplasty decreased in patients less than 2 years of age, while the rate remained constant in patients over age 2. Conclusion. The rate of pyeloplasty increased in PHIS hospitals from 1992 to 2011. Trends are due to an increase in surgery in infants younger than 2 years from 1992 to 1999, followed by a progressive surgical rate decline, characterized by a shift towards patients older than 2 years of age.

摘要

背景。在过去20年里,肾盂输尿管连接部梗阻(UPJ)的治疗方式发生了转变。尽管许多泌尿科医生注意到随着时间的推移肾盂成形术的实施数量有所减少,但实践中的变化性质尚未明确。在本研究中,我们利用一个全国性的儿童医院多机构数据库来评估过去20年中接受肾盂成形术患者的趋势以及手术重建率。

材料/方法。我们查询了儿科健康信息系统(PHIS)数据库中1992年至2011年间所有接受初次肾盂成形术的儿童。确定了临床变量,包括手术时的年龄、性别、住院时间(LOS)和地理区域。还计算了每10万名PHIS住院患者的年龄调整修复率。

结果。6013名患者纳入研究,其中71.6%为男性,64.2%在手术时年龄小于24个月。在研究期间,手术时的中位年龄从2 - 4个月增加到12 - 14个月(P < 0.01)。住院时间从中位数5天降至2天(P < 0.001)。从1992年到2011年,每10万名PHIS住院患者的手术率增加了10.6例肾盂成形术(P < 0.01)。肾盂成形术发生率最高的是东北部地区。1992年至1999年期间肾盂成形术实施数量的增加特定于年龄大于24个月的儿童,而在同一时期2岁以下婴儿的手术率保持不变。相比之下,从1999年到2011年,2岁以下患者的肾盂成形术发生率下降,而2岁以上患者的手术率保持不变。

结论。1992年至2011年期间,PHIS医院的肾盂成形术发生率增加。趋势是由于1992年至1999年期间2岁以下婴儿手术数量增加,随后手术率逐渐下降,其特征是向2岁以上患者转移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fc2/4052929/67cecbf4ce52/AU2014-142625.001.jpg

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