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小儿肾盂输尿管连接部梗阻围手术期管理的发展趋势:朝着更快康复和日间手术肾盂成形术努力

Evolving trends in peri-operative management of pediatric ureteropelvic junction obstruction: working towards quicker recovery and day surgery pyeloplasty.

作者信息

Rickard Mandy, Chua Michael, Kim Jin Kyu, Keefe Daniel T, Milford Karen, Hannick Jessica H, Dos Santos Joana, Koyle Martin A, Lorenzo Armando J

机构信息

Division of Urology, Department of Surgery, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.

Department of Urology, University of Toronto, Toronto, ON, Canada.

出版信息

World J Urol. 2021 Sep;39(9):3677-3684. doi: 10.1007/s00345-021-03621-9. Epub 2021 Mar 3.

Abstract

OBJECTIVE

To describe the evolution of practice patterns for pediatric pyeloplasty and determine how these changes have impacted length of stay (LOS), reoperation rates and return emergency department (ER) visits.

METHODS

We reviewed our pyeloplasty database from 2008 to 2020 at a quaternary pediatric referral center and we included children 0-18 years undergoing pyeloplasty. Variables captured included: age, sex, baseline and follow-up anteroposterior diameter (APD) and differential renal function (DRF). We also collected data on the use of drains, catheters and/or stents, nausea and vomiting prophylaxis, opioids, regional anesthesia, and non-opioid analgesia. Outcomes were LOS, reoperation rates and ER visits.

RESULTS

A total of 554 patients (565 kidneys) were included. Reoperation rate was 7%, redo rate 4% and ER visits 17%. There was a trend towards less opioids, indwelling catheters and internal stents and increasing non-opioid analgesia, externalized stents, and regional anesthesia during the study period. Same-day discharge (SDD) was possible for 88 (16%) children with no differences in reoperation or readmission rates between SDD and admitted (ADM). There was a difference in ER visits (21 [24%] vs. 26 [6%]; p = 0.04) for SDD vs. ADM, respectively. On multivariate analysis, the only predictor of ER visits was younger age. Patients < 7 months were more likely to present to ER (15/41; 37% vs. 6/47, 13%; p = 0.009). Multivariate analysis determined indwelling catheters and opioids were associated with ADM while dexamethasone and ketorolac with SDD.

CONCLUSION

Progressive changes in care have contributed to a shorter LOS and increasing rates of SDD for pyeloplasty patients. SDD appears to be feasible and does not result in higher complication rates. These data support the development of a pediatric pyeloplasty ERAS protocol to maximize quicker recovery and foster SDD as a goal.

摘要

目的

描述小儿肾盂成形术的手术方式演变,并确定这些变化如何影响住院时间(LOS)、再次手术率和急诊复诊率。

方法

我们回顾了一家四级儿科转诊中心2008年至2020年的肾盂成形术数据库,纳入了0至18岁接受肾盂成形术的儿童。记录的变量包括:年龄、性别、基线和随访前后径(APD)以及分肾功能(DRF)。我们还收集了关于引流管、导管和/或支架的使用、恶心和呕吐预防、阿片类药物、区域麻醉和非阿片类镇痛的数据。观察指标为住院时间、再次手术率和急诊复诊率。

结果

共纳入554例患者(565侧肾脏)。再次手术率为7%,二次手术率为4%,急诊复诊率为17%。在研究期间,阿片类药物、留置导管和内置支架的使用呈减少趋势,而非阿片类镇痛、外置支架和区域麻醉的使用呈增加趋势。88例(16%)儿童实现了当日出院(SDD),SDD组和入院(ADM)组的再次手术率或再入院率无差异。SDD组和ADM组的急诊复诊率存在差异(分别为21例[24%]和26例[6%];p = 0.04)。多因素分析显示,急诊复诊的唯一预测因素是年龄较小。7个月以下的患者更有可能前往急诊(15/41;37%对6/47,13%;p = 0.009)。多因素分析确定留置导管和阿片类药物与ADM相关,而地塞米松和酮咯酸与SDD相关。

结论

护理方式的逐步改变有助于缩短肾盂成形术患者的住院时间并提高当日出院率。当日出院似乎是可行的,且不会导致更高的并发症发生率。这些数据支持制定小儿肾盂成形术加速康复外科方案,以实现更快康复并将当日出院作为目标。

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