Igarashi Miho, Song Chorong, Ikei Harumi, Miyazaki Yoshifumi
Center for Environment, Health, and Field Sciences, Chiba University , Chiba, Japan .
J Altern Complement Med. 2014 Jul;20(7):545-9. doi: 10.1089/acm.2014.0100. Epub 2014 Jun 20.
To clarify the effect of olfactory stimulation with perilla essential oil on human prefrontal cortex activity using near-infrared time-resolved spectroscopy.
Single-center prospective study.
Nineteen female university students (mean age, 21.6 ± 1.5 years) participated in the study. Perilla essential oil was used as an olfactory stimulant and air as a control. Oxyhemoglobin concentrations in the prefrontal cortex were measured by using near-infrared time-resolved spectroscopy when the participants were presented with the stimulant or control. Emotional effects were subjectively evaluated by using a modified semantic differential method.
Olfactory stimulation with the perilla essential oil significantly reduced the oxyhemoglobin concentration in the prefrontal cortex. No significant differences in the feelings of comfort or relaxation, which strongly reflect human mental status, were observed between the perilla essential oil and control periods.
Olfactory stimulation with perilla essential oil reduced prefrontal cortex activity, thereby inducing physiologic relaxation.
使用近红外时间分辨光谱法阐明紫苏精油嗅觉刺激对人类前额叶皮质活动的影响。
单中心前瞻性研究。
19名女大学生（平均年龄21.6±1.5岁）参与了本研究。使用紫苏精油作为嗅觉刺激物，空气作为对照。当向参与者呈现刺激物或对照时，使用近红外时间分辨光谱法测量前额叶皮质中的氧合血红蛋白浓度。使用改良的语义差异法对情绪效应进行主观评估。
紫苏精油嗅觉刺激显著降低了前额叶皮质中的氧合血红蛋白浓度。在紫苏精油和对照阶段之间，在强烈反映人类心理状态的舒适或放松感方面未观察到显著差异。
紫苏精油嗅觉刺激降低了前额叶皮质活动，从而诱导生理放松。
