Center for Immunology, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55414, USA.
Center for Immunology, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55414, USA.
Immunity. 2014 Jun 19;40(6):859-60. doi: 10.1016/j.immuni.2014.05.008.
The common γ-chain (γc) is a key component of multiple cytokine receptors. In this issue of Immunity, Hong et al. (2014) demonstrate a unique function of γc as a secreted protein capable of inhibiting cytokine responses and promoting autoimmunity.
共同γ链(γc)是多种细胞因子受体的关键组成部分。在本期《免疫》杂志中,Hong 等人(2014)证明了 γc 作为一种分泌蛋白的独特功能,能够抑制细胞因子反应并促进自身免疫。