Casper Robert F, Gladanac Bojana
Division of Reproductive Sciences, University of Toronto, Toronto, Ontario, Canada; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.
Fertil Steril. 2014 Aug;102(2):319-20. doi: 10.1016/j.fertnstert.2014.04.053. Epub 2014 Jun 19.
Almost all forms of life have predictable daily or circadian rhythms in molecular, endocrine, and behavioral functions. In mammals, a central pacemaker located in the suprachiasmatic nuclei coordinates the timing of these rhythms. Daily light exposure that affects the retina of the eye directly influences this area, which is required to align endogenous processes to the appropriate time of day. The present "Views and Reviews" articles discuss the influence of circadian rhythms, especially nightly secretion of melatonin, on reproductive function and parturition. In addition, an examination is made of problems that arise from recurrent circadian rhythm disruption associated with changes in light exposure patterns common to modern day society. Finally, a possible solution to prevent disruptions in circadian phase markers by filtering out short wavelengths from nocturnal light is reviewed.
几乎所有生命形式在分子、内分泌和行为功能方面都有可预测的每日或昼夜节律。在哺乳动物中，位于视交叉上核的中央起搏器协调这些节律的时间。每日的光照直接影响眼睛的视网膜，进而影响这个区域，而这是使内源性过程与一天中的适当时间同步所必需的。本期“观点与综述”文章讨论了昼夜节律，尤其是褪黑素的夜间分泌，对生殖功能和分娩的影响。此外，还探讨了现代社会常见的光照模式变化所导致的反复昼夜节律紊乱引发的问题。最后，综述了一种通过滤除夜间光线中的短波长来防止昼夜节律相位标志物紊乱的可能解决方案。
