Vande Voort Jennifer L, He Jian-Ping, Jameson Nicole D, Merikangas Kathleen R
Genetic Epidemiology Research Branch in the Intramural Research Program at the National Institute of Mental Health (NIMH) in Bethesda, Maryland.
Genetic Epidemiology Research Branch in the Intramural Research Program at the National Institute of Mental Health (NIMH) in Bethesda, Maryland.
J Am Acad Child Adolesc Psychiatry. 2014 Jul;53(7):736-44. doi: 10.1016/j.jaac.2014.03.005. Epub 2014 Apr 23.
The present study aims to compare the prevalence and clinical correlates of DSM-IV versus DSM-5-defined attention-deficit/hyperactivity disorder (ADHD) and subtypes in a nationally representative sample of US youth based on the age-of-onset criterion.
The sample includes 1,894 participants 12 to 15 years of age from cross-sectional National Health and Nutrition Examination Survey (NHANES) surveys conducted from 2001 to 2004. Data on DSM-IV and DSM-5 criteria for ADHD were derived from administration of the parental ADHD module of the National Institute of Mental Health (NIMH) Diagnostic Interview Schedule for Children, Version IV (DISC-IV).
Extension of the age-of-onset criterion from 7 to 12 years led to an increase in the prevalence rate of ADHD from 7.38% (DSM-IV) to 10.84% (DSM-5). Youth with later age of onset did not differ from those with earlier age of onset in terms of severity and patterns of comorbidity. However, the group with later age of onset was more likely to be from lower income and ethnic minority families.
The comparability of the clinical significance of the early and later age-of-onset groups supports the DSM-5 extension of the age-of-onset criterion in ADHD.
本研究旨在基于发病年龄标准,比较在美国全国代表性青少年样本中,《精神疾病诊断与统计手册》第四版(DSM-IV)与第五版(DSM-5)定义的注意力缺陷多动障碍(ADHD)及其亚型的患病率和临床相关性。
样本包括来自2001年至2004年进行的横断面全国健康与营养检查调查(NHANES)的1894名12至15岁的参与者。ADHD的DSM-IV和DSM-5标准数据来自美国国立精神卫生研究所(NIMH)儿童诊断访谈量表第四版(DISC-IV)的家长ADHD模块。
将发病年龄标准从7岁延长至12岁导致ADHD患病率从7.38%(DSM-IV)增至10.84%(DSM-5)。发病年龄较晚的青少年在严重程度和共病模式方面与发病年龄较早的青少年没有差异。然而,发病年龄较晚的群体更有可能来自低收入和少数民族家庭。
发病年龄较早和较晚组临床意义的可比性支持了DSM-5对ADHD发病年龄标准的扩展。