Mehmood Akhter, Ismail Sameh R, Kabbani Mohamed S, Abu-Sulaiman Riyadh M, Najm Hani K
King Abdulaziz Medical City, King Saud University for Health Sciences, Department of Cardiac Sciences, National Guard Hospital Health Affairs, Riyadh.
J Saudi Heart Assoc. 2014 Jul;26(3):132-7. doi: 10.1016/j.jsha.2014.03.002. Epub 2014 Apr 3.
Infants with low body weight (LBW) following cardiac surgery are a major challenge for the post cardiac surgery care unit. It has been observed that post surgery outcome for LBW infants is worse compared to the outcome of normal body weight infants. A study was conducted to compare post operative course and outcome of infants with body weight of 2.2 kg or less against infants with normal body weight who underwent similar cardiac surgeries.
A retrospective review was performed for all infants below 2.2 kg who underwent cardiac operations at King Abdulaziz Cardiac Center from January 2001 to October 2011. Cases with LBW (Group A) were compared with matching group (Group B) of normal body weight infants who had similar cardiac surgeries and matching surgical risk category. The demographic, ICU parameters, complications, and short-term outcome of both groups were analyzed.
Two groups were formed, with 37 patients in Group A, and 39 patients in Group B. Except for weight (2.13 ± 0.08 kg in Group A vs 3.17 ± 0.2 kg in Group B), there was no statistical difference in demographic data between both groups. Cardiac procedures included coarctation repair, arterial switch, ventricular septal defect (VSD) repair, tetralogy of Fallot repair, systemic to pulmonary shunt and Norwood procedures. Patients in Group A had statistically significant difference from Group B in terms of bypass time (p = 0.01), duration of inotropes (p = 0.01), duration of mechanical ventilation (p = 0.004), number of re-intubations (p = 0.015), PCICU length of stay (p = 0.007), and hospital mortality: 13.5% in Group A vs 0% in Group B (p value 0.02).
Patients with LBW (<2.2 kg) underwent cardiac surgery with overall satisfactory results, but with increased risk of ICU morbidity and mortality.
心脏手术后低体重（LBW）婴儿是心脏手术后护理单元面临的一项重大挑战。据观察，与正常体重婴儿相比，LBW婴儿的术后结局更差。开展了一项研究，比较体重2.2千克及以下婴儿与接受类似心脏手术的正常体重婴儿的术后病程及结局。
对2001年1月至2011年10月在阿卜杜勒阿齐兹国王心脏中心接受心脏手术的所有体重低于2.2千克的婴儿进行回顾性研究。将LBW病例组（A组）与接受类似心脏手术且手术风险类别匹配的正常体重婴儿匹配组（B组）进行比较。分析了两组的人口统计学、重症监护病房（ICU）参数、并发症及短期结局。
形成了两组，A组37例患者，B组39例患者。除体重外（A组为2.13±0.08千克，B组为3.17±0.2千克），两组人口统计学数据无统计学差异。心脏手术包括缩窄修复术、动脉调转术、室间隔缺损（VSD）修复术、法洛四联症修复术、体肺分流术和诺伍德手术。A组患者在体外循环时间（p = 0.01）、血管活性药物使用时间（p = 0.01）、机械通气时间（p = 0.004）、再次插管次数（p = 0.015）、儿科重症监护病房（PCICU）住院时间（p = 0.007）以及医院死亡率方面与B组有统计学显著差异：A组为13.5%，B组为0%（p值0.02）。
LBW（<2.2千克）患者接受心脏手术，总体结果令人满意，但ICU发病和死亡风险增加。
