Liu Wuyi, Zhao Jingpeng
Department of Biology Sciences, Fuyang Normal College, China ; Department of Science and Technology Research, Fuyang Normal College, China.
Department of Animal Sciences, Shandong Agricultural University, China.
Saudi J Biol Sci. 2014 Jul;21(3):197-203. doi: 10.1016/j.sjbs.2014.01.005. Epub 2014 Feb 4.
As substantial progress has been achieved in modern poultry production with large-scale and intensive feeding and farming in recent years, stress becomes a vital factor affecting chicken growth, development, and production yield, especially the quality and quantity of skeletal muscle mass. The review was aimed to outline and understand the stress-related genetic regulatory mechanism, which significantly affects glucose metabolism regulation in chicken skeletal muscle tissues. Progress in current studies was summarized relevant to the molecular mechanism and regulatory pathways of glucose metabolism regulation under stress in chicken skeletal muscle tissues. Particularly, the elucidation of those concerned pathways promoted by insulin and insulin receptors would give key clues to the understanding of biological processes of stress response and glucose metabolism regulation under stress, as well as their later effects on chicken muscle development.
近年来，随着现代家禽生产通过大规模集约化饲养和养殖取得了重大进展，应激成为影响鸡生长、发育和产量的关键因素，尤其是骨骼肌质量的数量和质量。本综述旨在概述和理解与应激相关的遗传调控机制，该机制显著影响鸡骨骼肌组织中的葡萄糖代谢调节。总结了当前关于鸡骨骼肌组织应激状态下葡萄糖代谢调节的分子机制和调控途径的研究进展。特别是，对胰岛素和胰岛素受体所促进的相关途径的阐明，将为理解应激反应的生物学过程和应激状态下的葡萄糖代谢调节，以及它们随后对鸡肌肉发育的影响提供关键线索。
