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两性离子自组装单分子膜对蛋白质吸附及藻类细胞附着的影响。

Influence of zwitterionic SAMs on protein adsorption and the attachment of algal cells.

作者信息

Bauer Stella, Alles Maria, Finlay John A, Callow James A, Callow Maureen E, Rosenhahn Axel

机构信息

a Institute of Functional Interfaces , Karlsruhe Institute of Technology , Karlsruhe 76021 , Germany.

出版信息

J Biomater Sci Polym Ed. 2014;25(14-15):1530-9. doi: 10.1080/09205063.2014.929429. Epub 2014 Jun 23.

DOI:10.1080/09205063.2014.929429
PMID:24955504
Abstract

Zwitterionic polymers are non-fouling materials with immense potential for a range of biological applications. Here, we describe the resistance of zwitterionic self-assembled monolayers prepared from different solution ratios of positively and negatively charged thiols towards the adhesion of proteins, zoospores of the green alga Ulva linza, and cells of the unicellular alga Navicula perminuta. While mixed zwitterionic surfaces with a high hydrophilic nature significantly reduced the adhesion strength of the two algae, the positively and negatively charged components were far less effective.

摘要

两性离子聚合物是一类具有非污损特性的材料,在一系列生物应用中具有巨大潜力。在此,我们描述了由带正电和带负电硫醇的不同溶液比例制备的两性离子自组装单分子层对蛋白质、绿藻石莼游动孢子以及单细胞藻类微小舟形藻细胞黏附的抗性。虽然具有高亲水性的混合两性离子表面显著降低了两种藻类的黏附强度,但带正电和带负电的组分效果则要差得多。

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