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青少年特发性脊柱侧凸的最佳手术治疗:一项国际共识。

Optimal surgical care for adolescent idiopathic scoliosis: an international consensus.

作者信息

de Kleuver Marinus, Lewis Stephen J, Germscheid Niccole M, Kamper Steven J, Alanay Ahmet, Berven Sigurd H, Cheung Kenneth M, Ito Manabu, Lenke Lawrence G, Polly David W, Qiu Yong, van Tulder Maurits, Shaffrey Christopher

机构信息

Department of Orthopaedic Surgery, VU University Medicine Center, De Boelelaan 1117, 1081 HZ, Amsterdam, The Netherlands,

出版信息

Eur Spine J. 2014 Dec;23(12):2603-18. doi: 10.1007/s00586-014-3356-1. Epub 2014 Jun 24.

Abstract

PURPOSE

The surgical management of adolescent idiopathic scoliosis (AIS) has seen many developments in the last two decades. Little high-level evidence is available to support these changes and guide treatment. This study aimed to identify optimal operative care for adolescents with AIS curves between 40° and 90° Cobb angle.

METHODS

From July 2012 to April 2013, the AOSpine Knowledge Forum Deformity performed a modified Delphi survey where current expert opinion from 48 experienced deformity surgeons, representing 29 diverse countries, was gathered. Four rounds were performed: three web-based surveys and a final face-to-face meeting. Consensus was achieved with ≥ 70% agreement. Data were analyzed qualitatively and quantitatively.

RESULTS

Consensus of what constitutes optimal care was reached on greater than 60 aspects including: preoperative radiographs; posterior as opposed to anterior (endoscopic) surgical approaches; use of intraoperative spinal cord monitoring; use of local autologous bone (not iliac crest) for grafts; use of thoracic and lumbar pedicle screws; use of titanium anchor points; implant density of <80% for 40°-70° curves; and aspects of postoperative care. Variability in practice patterns was found where there was no consensus. In addition, there was consensus on what does not constitute optimal care, including: routine pre- and intraoperative traction; routine anterior release; use of bone morphogenetic proteins; and routine postoperative CT scanning.

CONCLUSIONS

International consensus was found on many aspects of what does and does not constitute optimal operative care for adolescents with AIS. In the absence of current high-level evidence, at present, these expert opinion findings will aid health care providers worldwide define appropriate care in their regions. Areas with no consensus provide excellent insight and priorities for future research.

摘要

目的

在过去二十年中,青少年特发性脊柱侧凸(AIS)的外科治疗有了许多进展。但几乎没有高级别证据来支持这些改变并指导治疗。本研究旨在确定对于Cobb角在40°至90°之间的AIS青少年患者的最佳手术治疗方案。

方法

2012年7月至2013年4月,AOSpine脊柱畸形知识论坛开展了一项改良的德尔菲调查,收集了来自29个不同国家的48位经验丰富的脊柱畸形外科医生的当前专家意见。共进行了四轮:三轮基于网络的调查和一次最后的面对面会议。当达成≥70%的一致意见时形成共识。对数据进行了定性和定量分析。

结果

在60多个方面达成了关于什么构成最佳治疗的共识,包括:术前X线片;与前路(内镜)手术方法相对的后路手术方法;术中脊髓监测的使用;使用局部自体骨(而非髂嵴骨)进行植骨;胸腰椎椎弓根螺钉的使用;钛锚点的使用;40° - 70°曲线的植入物密度<80%;以及术后护理的各个方面。在没有达成共识的地方发现了实践模式的差异。此外,对于什么不构成最佳治疗也达成了共识,包括:常规的术前和术中牵引;常规的前路松解;骨形态发生蛋白的使用;以及常规的术后CT扫描。

结论

对于AIS青少年患者,在构成和不构成最佳手术治疗的许多方面都达成了国际共识。在目前缺乏高级别证据的情况下,这些专家意见结果将有助于全球的医疗保健提供者在其所在地区确定合适的治疗方法。没有达成共识的领域为未来研究提供了极好的见解和优先事项。

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