Department of Pediatrics, McMaster Children's Hospital, McMaster University, Hamilton, ON, Canada.
BMC Pediatr. 2014 Jun 23;14:161. doi: 10.1186/1471-2431-14-161.
Over recent decades, the prevalence of pediatric obesity has increased markedly in developed and developing countries, and the impact of obesity on health throughout the lifespan has led to urgent calls for action. Family-based weight management interventions that emphasize healthy lifestyle changes can lead to modest improvements in weight status of children with obesity. However, these interventions are generally short in duration, reported in the context of randomized controlled trials and there are few reports of outcomes of these treatment approaches in the clinical setting. Answering these questions is critical for improving the care of children with obesity accessing outpatient health services for weight management. In response, the CANadian Pediatric Weight management Registry (CANPWR) was designed with the following three primary aims: 1. Document changes in anthropometric, lifestyle, behavioural, and obesity-related co-morbidities in children enrolled in Canadian pediatric weight management programs over a three-year period; 2. Characterize the individual-, family-, and program-level determinants of change in anthropometric and obesity-related co-morbidities; 3. Examine the individual-, family-, and program-level determinants of program attrition.
METHODS/DESIGN: This prospective cohort, multi-centre study will include children (2-17 years old; body mass index ≥85(th) percentile) enrolled in one of eight Canadian pediatric weight management centres. We will recruit 1,600 study participants over a three-year period. Data collection will occur at presentation and 6-, 12-, 24-, and 36-months follow-up. The primary study outcomes are BMI z-score and change in BMI z-score over time. Secondary outcomes include anthropometric (e.g., height, waist circumference,), cardiometabolic (e.g., blood pressure, lipid profile, glycemia), lifestyle (e.g., dietary intake, physical activity, sedentary activity), and psychosocial (e.g., health-related quality of life) variables. Potential determinants of change and program attrition will include individual-, family-, and program-level variables.
This study will enable our interdisciplinary team of clinicians, researchers, and trainees to address foundational issues regarding the management of pediatric obesity in Canada. It will also serve as a harmonized, evidence-based registry and platform for conducting future intervention research, which will ultimately enhance the weight management care provided to children with obesity and their families.
近几十年来，发达国家和发展中国家儿童肥胖的患病率显著增加，肥胖对整个生命周期健康的影响促使人们迫切呼吁采取行动。以强调健康生活方式改变为重点的基于家庭的体重管理干预措施，可以使肥胖儿童的体重状况得到适度改善。然而，这些干预措施的持续时间通常较短，仅在随机对照试验中报告，关于这些治疗方法在临床环境中的结果的报告很少。回答这些问题对于改善接受门诊保健服务进行体重管理的肥胖儿童的护理至关重要。有鉴于此，CANadian Pediatric Weight management Registry（CANPWR）的设计目的如下：1. 在三年内记录参加加拿大儿科体重管理计划的儿童的人体测量、生活方式、行为和肥胖相关合并症的变化；2. 描述人体测量和肥胖相关合并症变化的个体、家庭和计划层面决定因素；3. 检查计划退出的个体、家庭和计划层面决定因素。
方法/设计：这项前瞻性队列、多中心研究将包括在加拿大 8 个儿科体重管理中心之一注册的儿童（2-17 岁；体重指数≥第 85 百分位数）。我们将在三年内招募 1600 名研究参与者。数据收集将在就诊时以及 6、12、24 和 36 个月随访时进行。主要研究结果是 BMI z 分数和随时间的 BMI z 分数变化。次要结果包括人体测量（例如，身高、腰围）、心血管代谢（例如，血压、血脂谱、血糖）、生活方式（例如，饮食摄入、身体活动、久坐活动）和心理社会（例如，健康相关生活质量）变量。变化和计划退出的潜在决定因素将包括个体、家庭和计划层面的变量。
这项研究将使我们由临床医生、研究人员和学员组成的跨学科团队能够解决加拿大儿童肥胖管理的基本问题。它还将作为一个协调一致的、基于证据的登记处和平台，用于开展未来的干预研究，最终将提高为肥胖儿童及其家庭提供的体重管理护理。
