These authors contributed equally to this work.
Euro Surveill. 2014 Jun 12;19(23):20828. doi: 10.2807/1560-7917.es2014.19.23.20828.
The pseudoparticle virus neutralisation test (ppNT) and a conventional microneutralisation (MN) assay are specific for detecting antibodies to Middle East respiratory syndrome coronavirus (MERS-CoV) when used in seroepidemiological studies in animals. Genetically diverse MERS-CoV appear antigenically similar in MN tests. We confirm that MERS-CoV was circulating in dromedaries in Saudi Arabia in 1993. Preliminary data suggest that feral Australian dromedaries may be free of MERS-CoV but larger confirmatory studies are needed.
伪病毒中和试验(ppNT)和传统的微量中和(MN)试验在动物血清流行病学研究中特异性检测中东呼吸综合征冠状病毒(MERS-CoV)抗体。MN 试验中,遗传多样化的 MERS-CoV 似乎具有相似的抗原性。我们证实 1993 年 MERS-CoV 就在沙特阿拉伯的单峰驼中传播。初步数据表明,澳大利亚野生单峰驼可能没有 MERS-CoV,但需要更大规模的确认性研究。