Koibuchi Harumi, Omoto Kiyoka, Fukushima Noriyoshi, Toyotsuji Tomonori, Taniguchi Nobuyuki, Kawano Mikihiko
Departments of Clinical Laboratory Medicine (H.K., K.O., T.T., N.T., M.K.) and Laboratory Medicine (K.O., M.K.), Saitama Medical Center, and Department of Diagnostic Pathology (N.F., T.T.), Jichi Medical University, Saitama, Japan.
J Ultrasound Med. 2014 Jul;33(7):1299-303. doi: 10.7863/ultra.33.7.1299.
This report documents 3 pediatric papillary thyroid carcinoma cases with associated Hashimoto thyroiditis. In all 3 cases, hypoechoic nodules accompanied by multiple echogenic spots were noted on sonography of the thyroid. Hashimoto thyroiditis was suspected on the basis of positive thyroid autoantibody test results and pathologic examinations of thyroidectomy specimens, which revealed chronic thyroiditis with lymphocytic infiltration as the background of papillary thyroid carcinoma development. The potential for papillary carcinoma development warrants close follow-up, and meticulous sonographic examinations must be performed in children with Hashimoto thyroiditis.
本报告记录了3例伴有桥本甲状腺炎的儿童甲状腺乳头状癌病例。在所有3例病例中，甲状腺超声检查均发现低回声结节伴有多个强回声斑。根据甲状腺自身抗体检测结果阳性以及甲状腺切除标本的病理检查，怀疑为桥本甲状腺炎，病理检查显示慢性甲状腺炎伴淋巴细胞浸润，这是甲状腺乳头状癌发生的背景。甲状腺乳头状癌发生的可能性需要密切随访，对于患有桥本甲状腺炎的儿童必须进行细致的超声检查。
