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免疫功能低下患者因丝虫病引发的2型麻风反应。

Type 2 lepra reaction in an immunocompromised patient precipitated by filariasis.

作者信息

Singh Satyendra Kumar, Sharma Taniya, Rai Tulika, Prabhu Anand

机构信息

Department of Dermatology and Venereology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

出版信息

Indian J Sex Transm Dis AIDS. 2014 Jan;35(1):40-2. doi: 10.4103/0253-7184.132418.

Abstract

Though patients affected with both acquired immuno deficiency syndrome (AIDS) and leprosy commonly present with type 1 lepra reaction, there are few isolated reports of type 2 lepra reaction in retropositive patients affected with leprosy. We are presenting a case report of 35-year-old male affected with AIDS, tubercular lymphadenitis, and lepromatous leprosy with recurrent episodes of type 2 lepra reaction manifesting as erythema nodosum leprosum (ENL). Dipstick enzyme-linked immunosorbent assay (ELISA) for filarial antigen was also positive. The patient was treated with 100 mg thalidomide daily, 300 mg diethylcarbamazine, and modified multidrug therapy (MDT) for leprosy. He responded well and has not had any further reaction in the last 6 months.

摘要

虽然同时感染获得性免疫缺陷综合征(艾滋病)和麻风病的患者通常会出现1型麻风反应,但在麻风病逆转反应患者中,关于2型麻风反应的单独报道很少。我们报告一例35岁男性患者,患有艾滋病、结核性淋巴结炎和瘤型麻风,反复出现2型麻风反应,表现为麻风结节性红斑(ENL)。丝虫抗原快速检测酶联免疫吸附试验(ELISA)也呈阳性。该患者接受了每日100毫克沙利度胺、300毫克乙胺嗪治疗,并接受了改良的多药联合化疗(MDT)治疗麻风病。他反应良好,在过去6个月中没有出现任何进一步的反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2910/4066596/a678474992dd/IJSTD-35-40-g001.jpg

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