Heimlich H J, Carr G C
Heimlich Institute at Xavier University, Cincinnati 45207-1096.
Chest. 1989 May;95(5):1008-12. doi: 10.1378/chest.95.5.1008.
Over a six-year period, 200 patients requiring long-term oxygen therapy for hypoxemic lung disease underwent insertion of the micro-trach transtracheal catheter and were evaluated for one to seven years. The catheter requires no removal for cleaning; it is designed to function undisturbed within the trachea for six months between replacements. Transtracheal oxygen delivery and saline instillation were instituted immediately after inserting the device. Oxygen administration at a rate of 0.25 to 3 L/min was equivalent to 1 to 8 L/min delivered nasally. By the end of one year of follow-up, 12.5 percent of patients had dropped out of the study. Most patients comply with prescribed 24-hour-a-day oxygen use; in keeping with the NOTT study, life expectancy of emphysema patients may therefore be increased.
在六年的时间里，200名因低氧性肺部疾病需要长期吸氧治疗的患者接受了微气管切开术经气管导管的植入，并进行了1至7年的评估。该导管无需取出进行清洁；其设计目的是在两次更换之间在气管内不受干扰地工作六个月。在插入该装置后立即开始经气管输氧和滴注生理盐水。以0.25至3升/分钟的速率输氧相当于经鼻输氧1至8升/分钟。到随访一年结束时，12.5%的患者退出了研究。大多数患者遵守规定的每天24小时吸氧；因此，与NOTT研究一致，肺气肿患者的预期寿命可能会延长。
