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非遗传性 cherubism(一种疾病名称,可音译为“克勒伯病”等,具体可根据医学专业习惯确定准确译名)

Non-hereditary cherubism.

作者信息

Niranjan Babita, Shashikiran Nd, Singla Shilpy, Kasetty Sowmya

机构信息

Department of Pedodontics and Preventive Dentistry, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India.

Department of Oral Pathology, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India.

出版信息

J Oral Maxillofac Pathol. 2014 Jan;18(1):84-8. doi: 10.4103/0973-029X.131920.

Abstract

Cherubism is a self-limiting non-neoplastic autosomal dominant fibro-osseous disorder of the jaw usually found in children between 2-5 years of age. It occurs predominantly in boys and is characterized clinically by bilateral swelling of cheeks due to bony enlargement of the jaw that gives the patient a typical cherubic look. Cherubism may occur as solitary cases or in many members of family, often in multiple lesions. Radiographically the lesions appear as multilocular bilateral radiolucent areas. The present case report describes a 13-year-old female cherubic child with progressive swelling of cheeks.

摘要

cherubism是一种自限性的非肿瘤性常染色体显性遗传性颌骨纤维-骨疾病,通常见于2至5岁的儿童。它主要发生于男孩,临床特征为由于颌骨骨质增大导致双侧脸颊肿胀,使患者呈现出典型的天使面容。 cherubism可表现为散发病例,也可在家族中的多个成员中出现,常为多发病灶。影像学上,病灶表现为双侧多房性透射区。本病例报告描述了一名13岁患有cherubism的女性儿童,其脸颊进行性肿胀。

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