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双侧下颌骨和上颌骨受累的颌骨增大症:病例报告

Cherubism With Bilateral Mandible and Maxilla Involvement: A Case Report.

作者信息

Yu Zhaoyang, Zhai Miao, Gan Wei, Zhang Hong, Zhou Yuxia, Wen Haixia

机构信息

From the Department of Radiology and Pharmacy, Shandong Power Central Hospital (ZY, MZ, WG, HZ, HW); and Department of Gynaecology and Obstetrics, Women and Children Health Care Hospital of Shandong Province, Shandong, China (YZ).

出版信息

Medicine (Baltimore). 2015 Dec;94(49):e2120. doi: 10.1097/MD.0000000000002120.

Abstract

Cherubism is a rare, nonneoplastic, self-limiting fibro-osseous that occurs in children. Affected children usually appear normal at birth. Lesions are characterized by the replacement of bone with fibrovascular tissue containing many multinucleated giant cells. Most studies have reported cherubism to be familial and with bilateral involvement of the mandibles. The authors describe a nonfamilial case of cherubism, involving both the mandible and the maxilla, in a 4-year-old female child with slowly enlarging, painless, symmetrical swelling of both cheeks.Cherubism is a rare disease that is usually limited to the mandible, but the maxilla may be involved. Computed tomography scan and biopsy are helpful for early diagnosis.

摘要

cherubism是一种发生于儿童的罕见的、非肿瘤性的、自限性的纤维-骨病变。患病儿童出生时通常外观正常。病变的特征是骨被含有许多多核巨细胞的纤维血管组织所替代。大多数研究报告称cherubism是家族性的,且双侧下颌骨受累。作者描述了一例非家族性cherubism病例,累及一名4岁女童的下颌骨和上颌骨,其双颊缓慢增大、无痛、对称肿胀。cherubism是一种罕见疾病,通常局限于下颌骨,但上颌骨也可能受累。计算机断层扫描和活检有助于早期诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a07a/5008485/65157c71542b/medi-94-e2120-g001.jpg

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