Wichmann H E, Mueller W, Allhoff P, Beckmann M, Bocter N, Csicsaky M J, Jung M, Molik B, Schoeneberg G
Medizinisches Institut für Umwelthygiene, Auf'm Hennekamp, Düsseldorf, Federal Republic of Germany.
Environ Health Perspect. 1989 Feb;79:89-99. doi: 10.1289/ehp.897989.
In January 1985 a smog period occurred for 5 days in parts of West Germany, including the Rhur District. Mortality (24,000 death certificates), morbidity in hospitals (13,000 hospital admissions, 5400 outpatients, 1500 ambulance transports) and consultations in doctors' offices (1,250,000 contacts) were studied for a 6-week period including the smog episode and a time interval before and thereafter. The study region was the State of North Rhine-Westfalia (16 million inhabitants), but the analysis is restricted to the comparison of the polluted area and a control area (6 million inhabitants each). During the smog period, mortality and morbidity in hospitals increased in the polluted area, but there was no substantial increase in the control area. The increases were for the total number of deaths 8 vs. 2% (polluted area vs. control area), for hospital admissions 15 vs. 3%, for outpatients 12 vs. 5% and for deliveries by ambulance to hospitals 28% in the polluted area (not investigated in the control area). The effects were more pronounced for cardiovascular diseases than for respiratory diseases. The consultations in doctors' offices show a slight decrease (-2 vs. -4%). Regression analysis shows a moderate influence of temperature, but a strong influence of ambient air pollution. The maxima of the ambient concentrations are more important on the same day, whereas the influence of the daily averages is more pronounced after a delay of 2 days. The results are discussed considering other possible confounders such as indoor pollution and psychogenic influences of the alarm situation. In total, the study suggests moderate health effects due to increased air pollution during the smog episode.
1985年1月,西德部分地区,包括鲁尔区,出现了为期5天的烟雾期。对6周期间(包括烟雾事件期间以及前后的一个时间间隔)的死亡率(24000份死亡证明)、医院发病率(13000例住院、5400例门诊、1500例救护车转运)以及医生办公室的诊疗量(1250000次接触)进行了研究。研究区域是北莱茵 - 威斯特法伦州(1600万居民),但分析仅限于污染区和对照区(各600万居民)的比较。在烟雾期,污染区的死亡率和医院发病率上升,但对照区没有显著上升。上升幅度分别为:总死亡人数,污染区8%,对照区2%;住院人数,污染区15%,对照区3%;门诊人数,污染区12%,对照区5%;污染区救护车送往医院的分娩人数上升28%(对照区未调查)。心血管疾病的影响比呼吸道疾病更明显。医生办公室的诊疗量略有下降(-2%对-4%)。回归分析表明温度有适度影响,但环境空气污染影响强烈。当日环境浓度最大值影响更大,而日均浓度的影响在延迟2天后更明显。研究结果结合其他可能的混杂因素进行了讨论,如室内污染和警报情况的心理影响。总体而言,该研究表明烟雾事件期间空气污染增加对健康有适度影响。