Joy Er, Cornish Ja, Bootun R, Datta S, Chandran P
Wrexham Maelor Hospital, Wrexham, UK.
J Surg Case Rep. 2012 Jul 1;2012(7):3. doi: 10.1093/jscr/2012.7.3.
Carcinosarcomas are rare, malignant tumours normally arising from the uterus, ovaries and fallopian tubes and having both carcinomatous (epithelial cells) and sarcomatous (connective tissue) components. This case describes the first published case of a carcinosarcoma of the spleen presenting as microcytic anaemia. A 74 year old lady presented with a two stone weight loss and was found to have a microcytic, hypochromic anaemia. On examination there was a non-tender mass in the left upper quadrant and a CT scan demonstrated a mass arising from the spleen. She underwent a splenectomy, of which the histology confirmed carcinosarcoma. She is currently undergoing palliative chemotherapy. Although the condition is rare, it is important to be aware of this condition due to the poor prognosis and the unusual ways in which it can present.
癌肉瘤是一种罕见的恶性肿瘤,通常起源于子宫、卵巢和输卵管,同时具有癌性(上皮细胞)和肉瘤性(结缔组织)成分。本文报道了首例以小细胞贫血为表现的脾癌肉瘤病例。一名74岁女性因体重减轻两英石就诊,检查发现为小细胞低色素性贫血。体格检查发现左上腹有一非压痛性肿块,CT扫描显示脾脏有一肿块。她接受了脾切除术,组织学检查证实为癌肉瘤。她目前正在接受姑息化疗。尽管这种疾病罕见,但鉴于其预后较差以及可能出现的不寻常表现方式,了解这种疾病很重要。