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隆突性皮肤纤维肉瘤：一种罕见的皮肤肿瘤。

Dermatofibrosarcoma protuberans: A rare cutaneous tumour.

作者信息

Van Der Rijt R, Moradi P

机构信息

Prince of Wales Hospital, Sydney, Australia.

出版信息

J Surg Case Rep. 2012 Jul 1;2012(7):8. doi: 10.1093/jscr/2012.7.8.

DOI:10.1093/jscr/2012.7.8
PMID:24960733
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3649554/
Abstract

Dermatofibrosarcoma protuberans (DFSP) is an uncommon, locally aggressive, soft tissue tumour. Occurrence in the head and neck region is rare and facial presentations are even rarer. We present a case of a DFSP in a young gentleman with the oncological, functional and aesthetic challenges that arose from the case. We also reviewed the relevant literature on DFSP pertaining to the head and neck region and devised a treatment algorithm based on the best available evidence.

摘要

隆突性皮肤纤维肉瘤（DFSP）是一种罕见的、局部侵袭性软组织肿瘤。发生于头颈部区域较为罕见，而发生于面部的情况则更为罕见。我们报告了一例年轻男性的DFSP病例，以及该病例所带来的肿瘤学、功能和美学方面的挑战。我们还回顾了头颈部区域DFSP的相关文献，并根据现有最佳证据制定了一种治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1120/3649554/ffdc094bd16e/jscr-2012-7-8fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1120/3649554/3ab17d3b647e/jscr-2012-7-8fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1120/3649554/e29a19945593/jscr-2012-7-8fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1120/3649554/43c1af345d38/jscr-2012-7-8fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1120/3649554/1a5b8603829d/jscr-2012-7-8fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1120/3649554/ffdc094bd16e/jscr-2012-7-8fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1120/3649554/3ab17d3b647e/jscr-2012-7-8fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1120/3649554/e29a19945593/jscr-2012-7-8fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1120/3649554/43c1af345d38/jscr-2012-7-8fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1120/3649554/1a5b8603829d/jscr-2012-7-8fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1120/3649554/ffdc094bd16e/jscr-2012-7-8fig5.jpg

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Int J Surg Case Rep. 2013;4(1):134-8. doi: 10.1016/j.ijscr.2012.11.002. Epub 2012 Nov 10.

本文引用的文献

1
Advances in management of dermatofibrosarcoma protuberans.隆突性皮肤纤维肉瘤的治疗进展。
Dermatol Clin. 2011 Apr;29(2):191-200, viii. doi: 10.1016/j.det.2011.02.003.
2
Dermatofibrosarcoma protuberans: a partial response to imatinib therapy.隆突性皮肤纤维肉瘤：对伊马替尼治疗的部分反应。
Dermatol Surg. 2006 Mar;32(3):456-9. doi: 10.1111/j.1524-4725.2006.32090.x.
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Dermatofibrosarcoma protuberans treated at a single institution: a surgical disease with a high cure rate.单机构治疗隆突性皮肤纤维肉瘤：一种治愈率高的外科疾病。
J Clin Oncol. 2005 Oct 20;23(30):7669-75. doi: 10.1200/JCO.2005.02.5122.
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Genetics of dermatofibrosarcoma protuberans family of tumors: from ring chromosomes to tyrosine kinase inhibitor treatment.隆突性皮肤纤维肉瘤家族性肿瘤的遗传学：从环状染色体到酪氨酸激酶抑制剂治疗
Genes Chromosomes Cancer. 2003 May;37(1):1-19. doi: 10.1002/gcc.10202.
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Dermatofibrosarcoma protuberans of the head and neck.头颈部隆突性皮肤纤维肉瘤
Ann Surg Oncol. 2000 Oct;7(9):696-704. doi: 10.1007/s10434-000-0696-3.
6
Fibrosarcomatous ("high-grade") dermatofibrosarcoma protuberans: clinicopathologic and immunohistochemical study of a series of 41 cases with emphasis on prognostic significance.纤维肉瘤样（“高级别”）隆突性皮肤纤维肉瘤：41例系列病例的临床病理及免疫组化研究，重点关注预后意义。
Am J Surg Pathol. 1998 May;22(5):576-87. doi: 10.1097/00000478-199805000-00009.
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Radiation in management of patients with dermatofibrosarcoma protuberans.
J Clin Oncol. 1996 Aug;14(8):2365-9. doi: 10.1200/JCO.1996.14.8.2365.
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Dermatofibrosarcoma protuberans: an analysis of 86 cases--five with metastasis.隆突性皮肤纤维肉瘤：86例分析——5例伴有转移
Ann Surg. 1967 Nov;166(5):803-16. doi: 10.1097/00000658-196711000-00011.
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Dermatofibrosarcoma protuberans: treatment and prognosis.隆突性皮肤纤维肉瘤：治疗与预后
Eur J Surg Oncol. 1992 Jun;18(3):241-8.
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Dermatofibrosarcoma protuberans.隆突性皮肤纤维肉瘤
CA Cancer J Clin. 1992 Mar-Apr;42(2):116-25. doi: 10.3322/canjclin.42.2.116.