Romero Fr, Zanini Ma, Ducati Lg, Gabarra Rc, Haddad Gr, de Souza V
Neurosurgery Division, São Paulo State University, UNESP, Botucatu, Brazil.
J Surg Case Rep. 2012 Sep 1;2012(9):9. doi: 10.1093/jscr/2012.9.9.
The authors report a case of 36-year-old woman presented with epileptic seizures and headaches. Magnetic resonance imaging (MRI) revealed an enhancing lesion with surrounding edema and mild mass effect in the left frontal lobe. Stereotactic brain biopsy demonstrated intraparenchymal granulomas surrounding S. mansoni eggs. Praziquantel was started (60mg/kg of body weight, in a single dose), followed by Prednisone (80mg/day) for seven days to treat the cerebral edema. The patient's symptoms resolved following medical treatment and the follow-up MRI yielded normal findings.
作者报告了一例36岁女性,出现癫痫发作和头痛症状。磁共振成像(MRI)显示左额叶有一个强化病灶,周围有水肿及轻度占位效应。立体定向脑活检显示脑实质内有围绕曼氏血吸虫卵的肉芽肿。开始使用吡喹酮(60mg/kg体重,单次剂量)治疗,随后使用泼尼松(80mg/天)治疗7天以治疗脑水肿。经药物治疗后患者症状缓解,后续MRI检查结果正常。