Bry K, Hallman M
Department of Pediatrics, University of Helsinki, Finland.
J Perinatol. 1989 Mar;9(1):60-5.
According to the current view, the fetal membranes and the amniotic fluid are central in transmission of signals resulting in labor and delivery. It has also become increasingly evident that although preterm and term labor share common pathways in activation of uterine contractions, the regulatory aspects are fundamentally different. The present article is a brief overview focusing on the participation of prostaglandins in human term and preterm labor. The involvement of bacteria in preterm labor is presented. In addition, it is proposed that inflammatory polymorphonuclear leukocytes promote preterm labor by activating prostaglandin production from human fetal membranes.
根据目前的观点，胎膜和羊水在引发分娩的信号传递中起核心作用。越来越明显的是，尽管早产和足月产在子宫收缩激活方面有共同途径，但调节方面却有根本差异。本文是一篇简要综述，重点关注前列腺素在人类足月产和早产中的作用。文中介绍了细菌在早产中的作用。此外，有人提出炎症性多形核白细胞通过激活人胎膜产生前列腺素促进早产。
