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在血液传播病毒研究中维持黑猩猩的适宜条件:流行病学和社会心理视角

Appropriate conditions for maintenance of chimpanzees in studies with blood-borne viruses: an epidemiologic and psychosocial perspective.

作者信息

Prince A M, Goodall J, Brotman B, Dienske H, Schellekens H, Eichberg J W

机构信息

Laboratory of Virology, Lindsley F. Kimball Research Institute, New York Blood Center, New York.

出版信息

J Med Primatol. 1989;18(1):27-42.

PMID:2496232
Abstract

Based on the know epidemiology of the viruses that account for the bulk of the need for chimpanzees in biomedical research--hepatitis B virus (HBV), non-A, non-B (NANB) hepatitis virus, and human immunodeficiency virus (HIV)--as well as the psychosocial needs of this species, requirements for appropriate isolation conditions for these animals have been reviewed. We believe that animals should generally be housed in groups of at least two in the same cage, and that cages encased in solid-walled isolator boxes for housing of single chimpanzees are unnecessary for virologically adequate isolation for studies of HBV, NANB and HIV, and cause sensory and psychosocial deprivation, which contravenes their psychological well-being.

摘要

基于生物医学研究中对黑猩猩有大量需求的病毒(乙型肝炎病毒(HBV)、非甲非乙型(NANB)肝炎病毒和人类免疫缺陷病毒(HIV))的已知流行病学情况,以及该物种的心理社会需求,对这些动物适当隔离条件的要求进行了审查。我们认为,动物一般应至少两只一组饲养在同一个笼子里,对于HBV、NANB和HIV研究而言,用实心壁隔离箱包裹的用于单只黑猩猩饲养的笼子对于病毒学上充分的隔离来说是不必要的,并且会导致感官和心理社会剥夺,这违背了它们的心理健康。

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Appropriate conditions for maintenance of chimpanzees in studies with blood-borne viruses: an epidemiologic and psychosocial perspective.在血液传播病毒研究中维持黑猩猩的适宜条件:流行病学和社会心理视角
J Med Primatol. 1989;18(1):27-42.
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The ethical approach to AIDS: a bibliographical review.艾滋病的伦理方法:文献综述。
J Med Ethics. 1990 Mar;16(1):14-27. doi: 10.1136/jme.16.1.14.
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Ethical problems raised by anti-HIV vaccination.抗HIV疫苗引发的伦理问题。
Eur J Epidemiol. 1991 Mar;7(2):147-53. doi: 10.1007/BF00237358.