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一项针对印度人群皮肤至蛛网膜下腔深度的前瞻性观察研究。

A prospective observational study of skin to subarachnoid space depth in the Indian population.

作者信息

Prakash Smita, Mullick Parul, Chopra Pooja, Kumar Santosh, Singh Rajvir, Gogia Anoop R

机构信息

Department of Anaesthesia and Intensive Care, Vardhman Mahavir Medical College and Safdarjang Hospital, New Delhi, India.

Department of Medical Research Cardiology, HMC, Doha, Qatar.

出版信息

Indian J Anaesth. 2014 Mar;58(2):165-70. doi: 10.4103/0019-5049.130819.

Abstract

BACKGROUND AND AIMS

A pre-puncture estimate of skin to subarachnoid space depth (SSD) may guide spinal needle placement and reduce complications associated with lumbar puncture. Our aim was to determine (1) The SSD in Indian males, females, parturients and the overall population; (2) To derive formulae for predicting SSD and (3) To determine which previously suggested formula best suited our population.

METHODS

In this prospective, observational study, 800 adult Indian patients undergoing surgery under spinal anaesthesia were divided into three groups: Males (Group M), females (Group F) and parturients (Group PF). SSD was measured after lumbar puncture. The relationship between SSD and patient characteristics was studied and statistical models were used to derive formula for predicting SSD. Statistical analysis included One-way ANOVA with post hoc analysis, forward stepwise multivariate regression analysis and paired t-tests.

RESULTS

Mean SSD was 4.71 ± 0.70 cm in the overall population. SSD in adult males (4.81 ± 0.68 cm) was significantly longer than that observed in females (4.55 ± 0.66 cm) but was comparable with SSD in parturients (4.73 ± 0.73 cm). Formula for predicting SSD in the overall population was 2.71 + 0.09 × Body Mass Index (BMI). Stocker's formula when applied correlated best with the observed SSD. Formulae were derived for the three groups.

CONCLUSIONS

We found gender-based differences in SSD, with SSD in males being significantly greater than that observed in the female population. SSD correlated with BMI in the parturient and the overall population. Amongst the previously proposed formulae, Stocker's formula was most accurate in predicting SSD in our population.

摘要

背景与目的

穿刺前对皮肤至蛛网膜下腔深度(SSD)进行评估,可能有助于指导脊髓穿刺针的放置,并减少与腰椎穿刺相关的并发症。我们的目的是确定:(1)印度男性、女性、产妇及总体人群的SSD;(2)推导预测SSD的公式;(3)确定之前提出的哪个公式最适合我们的人群。

方法

在这项前瞻性观察研究中,800例接受脊髓麻醉下手术的成年印度患者被分为三组:男性(M组)、女性(F组)和产妇(PF组)。在腰椎穿刺后测量SSD。研究SSD与患者特征之间的关系,并使用统计模型推导预测SSD的公式。统计分析包括单因素方差分析及事后分析、向前逐步多元回归分析和配对t检验。

结果

总体人群的平均SSD为4.71±0.70cm。成年男性的SSD(4.81±0.68cm)显著长于女性(4.55±0.66cm),但与产妇的SSD(4.73±0.73cm)相当。总体人群中预测SSD的公式为2.71 + 0.09×体重指数(BMI)。应用斯托克公式时与观察到的SSD相关性最佳。为三组分别推导了公式。

结论

我们发现SSD存在性别差异,男性的SSD显著大于女性人群。产妇和总体人群的SSD与BMI相关。在之前提出的公式中,斯托克公式在预测我们人群的SSD方面最准确。

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