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测量埃及人群中皮肤至蛛网膜下腔的深度:一项前瞻性队列研究。

Measuring skin to subarachnoid space depth in Egyptian population: A prospective cohort study.

作者信息

Taman Hani Ibrahim, Farid Ahmed Mohamed, Abdelghaffar Waleed Mohamed

机构信息

Department of Anesthesia and Surgical Intensive Care, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Department of Gynecology and Obstetrics, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt.

出版信息

Anesth Essays Res. 2016 Sep-Dec;10(3):468-472. doi: 10.4103/0259-1162.179312.

Abstract

BACKGROUND

Lumbar puncture is a difficult medical skill and is used for administering subarachnoid anesthetic medications. Estimation of skin to subarachnoid space depth (SSD) helps to reduce post spinal anesthetic complications.

AIMS

To measure the SDD in overall Egyptian population and to find a formula for predicting SSD in Egyptian patients.

SETTINGS AND DESIGN

Four hundred patients of American Society of Anesthesiologist class I and II adult Egyptian patients undergoing surgery using spinal anesthesia in general and obstetric surgery unit, Mansoura University main hospital, were included in this prospective, observational study.

SUBJECTS AND METHODS

Patients were divided into three groups: Males (Group M), nonpregnant females (Group F), and pregnant females (Group PF). SSD was measured after performing lumbar puncture. The relationship between SSD and patient characteristics was studied; correlated and statistical analysis was used to find a formula for predicting SSD.

STATISTICAL ANALYSIS USED

Statistical analysis was done using Statistical Package for Social Sciences (SPSS 19.0, Chicago, IL, USA). One-way ANOVA with (Bonferroni correction factor) analysis was applied to compare the three groups. All the covariates in the study further were taken for multivariate analysis. Multivariate regression analysis was performed to evaluate important covariates influencing SSD for each group separately.

RESULTS

Mean SSD was 4.99 ± 0.48 cm in the overall population. SSD in adult males (4.93 ± 0.47 cm) was significantly longer than that observed in females (4.22 ± 0.49 cm) but was comparable with SSD in parturient (4.32 ± 0.47 cm). Formula for predicting SSD in the overall population was 2.1+ (0.009 × height) + (0.03 × weight) + (0.02 × body mass index [BMI]) + (0.15 × body surface area [BSA]). Craig's formula when applied correlated best with the observed SSD.

CONCLUSIONS

SSD in adult males was significantly longer than that in both pregnant and nonpregnant females, but it was nearly the same in pregnant and nonpregnant females. SSD in Egyptian population can be calculated based on height, weight, BMI, and BSA. Craig's formula was the most suitable to be applied to Egyptian population.

摘要

背景

腰椎穿刺是一项难度较大的医学操作技能,用于蛛网膜下腔麻醉药物的给药。估算皮肤至蛛网膜下腔深度(SSD)有助于减少脊麻后并发症。

目的

测量埃及总体人群的SSD,并找出预测埃及患者SSD的公式。

设置与设计

本前瞻性观察性研究纳入了曼苏拉大学主医院普通外科和产科手术单元中400例接受脊麻手术的美国麻醉医师协会I级和II级成年埃及患者。

研究对象与方法

患者分为三组:男性(M组)、非孕女性(F组)和孕女性(PF组)。腰椎穿刺后测量SSD。研究SSD与患者特征之间的关系;采用相关性和统计分析来找出预测SSD的公式。

所用统计分析方法

使用社会科学统计软件包(SPSS 19.0,美国伊利诺伊州芝加哥)进行统计分析。采用单因素方差分析及(Bonferroni校正因子)分析来比较三组。研究中的所有协变量进一步进行多因素分析。分别对每组进行多因素回归分析,以评估影响SSD的重要协变量。

结果

总体人群的平均SSD为4.99±0.48 cm。成年男性的SSD(4.93±0.47 cm)显著长于女性(4.22±0.49 cm),但与产妇的SSD(4.32±0.47 cm)相当。预测总体人群SSD的公式为2.1 +(0.009×身高)+(0.03×体重)+(0.02×体重指数[BMI])+(0.15×体表面积[BSA])。应用Craig公式时与观察到的SSD相关性最佳。

结论

成年男性的SSD显著长于孕女性和非孕女性,但孕女性和非孕女性的SSD几乎相同。埃及人群的SSD可根据身高、体重、BMI和BSA进行计算。Craig公式最适用于埃及人群。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4a8/5062226/2523c1e302c1/AER-10-468-g003.jpg

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