Maschmeyer Georg, Patterson Thomas F
Department of Hematology, Oncology and Palliative Care, Klinikum Ernst von Bergmann, Academic Teaching Hospital of the Charité University Medicine of Berlin, Potsdam, Germany.
Mycoses. 2014 Nov;57(11):645-51. doi: 10.1111/myc.12213. Epub 2014 Jun 25.
Evidence-based clinical pathways to direct antifungal treatment options in patients with breakthrough fungal infections during current systemic antifungal therapy are not available. Nonetheless, for defined settings of such breakthrough infections approaches to management can be recommended based on clinical, epidemiological, pharmacological and in vitro susceptibility data.
目前尚无基于循证的临床路径来指导接受全身性抗真菌治疗期间发生突破性真菌感染的患者选择抗真菌治疗方案。尽管如此,对于此类突破性感染的特定情况,可根据临床、流行病学、药理学及体外药敏数据推荐管理方法。