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一名免疫功能正常患者发生垂体窝曲霉菌瘤,表现类似浸润性肿瘤,此为一罕见病例。

An unusual case of a pituitary fossa aspergilloma in an immunocompetent patient mimicking infiltrative tumour.

作者信息

Ahmadzai Hasib, Raley Darryl Alan, Masters Lynette, Davies Mark

机构信息

Faculty of Medicine, University of New South Wales (UNSW), Sydney, Australia Department of Neurology and Neurosurgery, St George Hospital, Kogarah, Australia

Department of Neurology and Neurosurgery, St George Hospital, Kogarah, Australia.

出版信息

J Surg Case Rep. 2013 Apr 18;2013(4):rjt018. doi: 10.1093/jscr/rjt018.

Abstract

Sellar aspergillosis is a rare infection commonly mistaken for a pituitary tumour. We present a rare case of pituitary fossa Aspergillus fumigatus mycetoma in an immunocompetent 90-year-old female, who presented with headaches. Magnetic resonance imaging scans demonstrated an enhancing pituitary fossa mass that appeared to infiltrate the sphenoid sinus, suggestive of an invasive tumour. Stereotactic trans-sphenoidal resection confirmed localized A. fumigatus infection. The abscess was debrided and the dura was left intact. Her headaches resolved post-operatively and she was treated with voriconazole. This indicates that aspergilloma should be considered as a differential for an unexplained pituitary lesion even in elderly immunocompetent patients.

摘要

鞍区曲霉菌病是一种罕见的感染,常被误诊为垂体肿瘤。我们报告一例罕见的垂体窝烟曲霉菌瘤病例,患者为一名90岁免疫功能正常的女性,表现为头痛。磁共振成像扫描显示垂体窝有一强化肿块,似乎侵犯了蝶窦,提示为侵袭性肿瘤。立体定向经蝶窦切除术证实为局限性烟曲霉菌感染。脓肿被清创,硬脑膜保持完整。她术后头痛缓解,并接受了伏立康唑治疗。这表明,即使在老年免疫功能正常的患者中,曲霉菌瘤也应被视为不明原因垂体病变的鉴别诊断之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcbc/3635217/7e17148397b2/rjt01801.jpg

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